Selectivity of mRNA degradation by autophagy in yeast

Autophagic degradation of proteins and organelles is well studied, but the role of autophagy in RNA regulation is unclear. Here, the authors profile mRNAs targeted to the vacuole in yeast and observe autophagy-mediated mRNA degradation is not random but rather is a preferential process.

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Autores principales: Shiho Makino, Tomoko Kawamata, Shintaro Iwasaki, Yoshinori Ohsumi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/421dd11f73434bc1bdbdf632a13eda6f
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spelling oai:doaj.org-article:421dd11f73434bc1bdbdf632a13eda6f2021-12-02T16:45:10ZSelectivity of mRNA degradation by autophagy in yeast10.1038/s41467-021-22574-62041-1723https://doaj.org/article/421dd11f73434bc1bdbdf632a13eda6f2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22574-6https://doaj.org/toc/2041-1723Autophagic degradation of proteins and organelles is well studied, but the role of autophagy in RNA regulation is unclear. Here, the authors profile mRNAs targeted to the vacuole in yeast and observe autophagy-mediated mRNA degradation is not random but rather is a preferential process.Shiho MakinoTomoko KawamataShintaro IwasakiYoshinori OhsumiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shiho Makino
Tomoko Kawamata
Shintaro Iwasaki
Yoshinori Ohsumi
Selectivity of mRNA degradation by autophagy in yeast
description Autophagic degradation of proteins and organelles is well studied, but the role of autophagy in RNA regulation is unclear. Here, the authors profile mRNAs targeted to the vacuole in yeast and observe autophagy-mediated mRNA degradation is not random but rather is a preferential process.
format article
author Shiho Makino
Tomoko Kawamata
Shintaro Iwasaki
Yoshinori Ohsumi
author_facet Shiho Makino
Tomoko Kawamata
Shintaro Iwasaki
Yoshinori Ohsumi
author_sort Shiho Makino
title Selectivity of mRNA degradation by autophagy in yeast
title_short Selectivity of mRNA degradation by autophagy in yeast
title_full Selectivity of mRNA degradation by autophagy in yeast
title_fullStr Selectivity of mRNA degradation by autophagy in yeast
title_full_unstemmed Selectivity of mRNA degradation by autophagy in yeast
title_sort selectivity of mrna degradation by autophagy in yeast
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/421dd11f73434bc1bdbdf632a13eda6f
work_keys_str_mv AT shihomakino selectivityofmrnadegradationbyautophagyinyeast
AT tomokokawamata selectivityofmrnadegradationbyautophagyinyeast
AT shintaroiwasaki selectivityofmrnadegradationbyautophagyinyeast
AT yoshinoriohsumi selectivityofmrnadegradationbyautophagyinyeast
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