Selectivity of mRNA degradation by autophagy in yeast
Autophagic degradation of proteins and organelles is well studied, but the role of autophagy in RNA regulation is unclear. Here, the authors profile mRNAs targeted to the vacuole in yeast and observe autophagy-mediated mRNA degradation is not random but rather is a preferential process.
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Nature Portfolio
2021
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oai:doaj.org-article:421dd11f73434bc1bdbdf632a13eda6f2021-12-02T16:45:10ZSelectivity of mRNA degradation by autophagy in yeast10.1038/s41467-021-22574-62041-1723https://doaj.org/article/421dd11f73434bc1bdbdf632a13eda6f2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22574-6https://doaj.org/toc/2041-1723Autophagic degradation of proteins and organelles is well studied, but the role of autophagy in RNA regulation is unclear. Here, the authors profile mRNAs targeted to the vacuole in yeast and observe autophagy-mediated mRNA degradation is not random but rather is a preferential process.Shiho MakinoTomoko KawamataShintaro IwasakiYoshinori OhsumiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021) |
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Science Q Shiho Makino Tomoko Kawamata Shintaro Iwasaki Yoshinori Ohsumi Selectivity of mRNA degradation by autophagy in yeast |
description |
Autophagic degradation of proteins and organelles is well studied, but the role of autophagy in RNA regulation is unclear. Here, the authors profile mRNAs targeted to the vacuole in yeast and observe autophagy-mediated mRNA degradation is not random but rather is a preferential process. |
format |
article |
author |
Shiho Makino Tomoko Kawamata Shintaro Iwasaki Yoshinori Ohsumi |
author_facet |
Shiho Makino Tomoko Kawamata Shintaro Iwasaki Yoshinori Ohsumi |
author_sort |
Shiho Makino |
title |
Selectivity of mRNA degradation by autophagy in yeast |
title_short |
Selectivity of mRNA degradation by autophagy in yeast |
title_full |
Selectivity of mRNA degradation by autophagy in yeast |
title_fullStr |
Selectivity of mRNA degradation by autophagy in yeast |
title_full_unstemmed |
Selectivity of mRNA degradation by autophagy in yeast |
title_sort |
selectivity of mrna degradation by autophagy in yeast |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/421dd11f73434bc1bdbdf632a13eda6f |
work_keys_str_mv |
AT shihomakino selectivityofmrnadegradationbyautophagyinyeast AT tomokokawamata selectivityofmrnadegradationbyautophagyinyeast AT shintaroiwasaki selectivityofmrnadegradationbyautophagyinyeast AT yoshinoriohsumi selectivityofmrnadegradationbyautophagyinyeast |
_version_ |
1718383509653946368 |