Proteomics of protein trafficking by in vivo tissue-specific labeling

The network of proteins secreted for interorgan communication is poorly understood. Here, the authors develop a method, based on protein labeling, to study cell-specific secretomes and interorgan protein trafficking, and demonstrate their approach in Drosophila and mouse models.

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Autores principales: Ilia A. Droujinine, Amanda S. Meyer, Dan Wang, Namrata D. Udeshi, Yanhui Hu, David Rocco, Jill A. McMahon, Rui Yang, JinJin Guo, Luye Mu, Dominique K. Carey, Tanya Svinkina, Rebecca Zeng, Tess Branon, Areya Tabatabai, Justin A. Bosch, John M. Asara, Alice Y. Ting, Steven A. Carr, Andrew P. McMahon, Norbert Perrimon
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/422c9afa42b14702bb8a2d8be8a9fe8e
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spelling oai:doaj.org-article:422c9afa42b14702bb8a2d8be8a9fe8e2021-12-02T16:45:10ZProteomics of protein trafficking by in vivo tissue-specific labeling10.1038/s41467-021-22599-x2041-1723https://doaj.org/article/422c9afa42b14702bb8a2d8be8a9fe8e2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22599-xhttps://doaj.org/toc/2041-1723The network of proteins secreted for interorgan communication is poorly understood. Here, the authors develop a method, based on protein labeling, to study cell-specific secretomes and interorgan protein trafficking, and demonstrate their approach in Drosophila and mouse models.Ilia A. DroujinineAmanda S. MeyerDan WangNamrata D. UdeshiYanhui HuDavid RoccoJill A. McMahonRui YangJinJin GuoLuye MuDominique K. CareyTanya SvinkinaRebecca ZengTess BranonAreya TabatabaiJustin A. BoschJohn M. AsaraAlice Y. TingSteven A. CarrAndrew P. McMahonNorbert PerrimonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ilia A. Droujinine
Amanda S. Meyer
Dan Wang
Namrata D. Udeshi
Yanhui Hu
David Rocco
Jill A. McMahon
Rui Yang
JinJin Guo
Luye Mu
Dominique K. Carey
Tanya Svinkina
Rebecca Zeng
Tess Branon
Areya Tabatabai
Justin A. Bosch
John M. Asara
Alice Y. Ting
Steven A. Carr
Andrew P. McMahon
Norbert Perrimon
Proteomics of protein trafficking by in vivo tissue-specific labeling
description The network of proteins secreted for interorgan communication is poorly understood. Here, the authors develop a method, based on protein labeling, to study cell-specific secretomes and interorgan protein trafficking, and demonstrate their approach in Drosophila and mouse models.
format article
author Ilia A. Droujinine
Amanda S. Meyer
Dan Wang
Namrata D. Udeshi
Yanhui Hu
David Rocco
Jill A. McMahon
Rui Yang
JinJin Guo
Luye Mu
Dominique K. Carey
Tanya Svinkina
Rebecca Zeng
Tess Branon
Areya Tabatabai
Justin A. Bosch
John M. Asara
Alice Y. Ting
Steven A. Carr
Andrew P. McMahon
Norbert Perrimon
author_facet Ilia A. Droujinine
Amanda S. Meyer
Dan Wang
Namrata D. Udeshi
Yanhui Hu
David Rocco
Jill A. McMahon
Rui Yang
JinJin Guo
Luye Mu
Dominique K. Carey
Tanya Svinkina
Rebecca Zeng
Tess Branon
Areya Tabatabai
Justin A. Bosch
John M. Asara
Alice Y. Ting
Steven A. Carr
Andrew P. McMahon
Norbert Perrimon
author_sort Ilia A. Droujinine
title Proteomics of protein trafficking by in vivo tissue-specific labeling
title_short Proteomics of protein trafficking by in vivo tissue-specific labeling
title_full Proteomics of protein trafficking by in vivo tissue-specific labeling
title_fullStr Proteomics of protein trafficking by in vivo tissue-specific labeling
title_full_unstemmed Proteomics of protein trafficking by in vivo tissue-specific labeling
title_sort proteomics of protein trafficking by in vivo tissue-specific labeling
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/422c9afa42b14702bb8a2d8be8a9fe8e
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