Down-regulated NOD2 by immunosuppressants in peripheral blood cells in patients with SLE reduces the muramyl dipeptide-induced IL-10 production.

Down-regulated NOD2 by immunosuppressants in peripheral blood cells in patients with SLE reduces the muramyl dipeptide-induced IL-10 production.

<h4>Background</h4>Pattern recognition receptors (PRRs) such as Toll-like receptors are aberrantly expressed of peripheral blood mononuclear cells (PBMCs) in systemic lupus erythematosus (SLE) patients, for playing immunopathological roles.<h4>Methodology/principal findings</h4&...

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Autores principales: Shui-Lian Yu, Chun-Kwok Wong, Purple Tsz-Yan Wong, Da-Peng Chen, Cheuk-Chun Szeto, Edmund K Li, Lai-Shan Tam
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/4230a8be77d74e64bec7f94339a74705
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