Deconvoluting hepatic processing of carbon nanotubes

Application of carbon nanotubes as drug delivery carriers is stalled by uncertainties over their distribution and toxicity in vivo. Here, the authors use animal models to show that, while the bulk of nanotubes is renally cleared, a fraction can be eliminated through an alternative hepatobiliary path...

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Autores principales:	Simone Alidori, Robert L. Bowman, Dmitry Yarilin, Yevgeniy Romin, Afsar Barlas, J. Justin Mulvey, Sho Fujisawa, Ke Xu, Alessandro Ruggiero, Vladimir Riabov, Daniel L. J. Thorek, Hans David S. Ulmert, Elliott J. Brea, Katja Behling, Julia Kzhyshkowska, Katia Manova-Todorova, David A. Scheinberg, Michael R. McDevitt
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/423150c700094e65a6244050ab69116e
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spelling	oai:doaj.org-article:423150c700094e65a6244050ab69116e2021-12-02T16:57:05ZDeconvoluting hepatic processing of carbon nanotubes10.1038/ncomms123432041-1723https://doaj.org/article/423150c700094e65a6244050ab69116e2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12343https://doaj.org/toc/2041-1723Application of carbon nanotubes as drug delivery carriers is stalled by uncertainties over their distribution and toxicity in vivo. Here, the authors use animal models to show that, while the bulk of nanotubes is renally cleared, a fraction can be eliminated through an alternative hepatobiliary pathway.Simone AlidoriRobert L. BowmanDmitry YarilinYevgeniy RominAfsar BarlasJ. Justin MulveySho FujisawaKe XuAlessandro RuggieroVladimir RiabovDaniel L. J. ThorekHans David S. UlmertElliott J. BreaKatja BehlingJulia KzhyshkowskaKatia Manova-TodorovaDavid A. ScheinbergMichael R. McDevittNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Simone Alidori Robert L. Bowman Dmitry Yarilin Yevgeniy Romin Afsar Barlas J. Justin Mulvey Sho Fujisawa Ke Xu Alessandro Ruggiero Vladimir Riabov Daniel L. J. Thorek Hans David S. Ulmert Elliott J. Brea Katja Behling Julia Kzhyshkowska Katia Manova-Todorova David A. Scheinberg Michael R. McDevitt Deconvoluting hepatic processing of carbon nanotubes
description	Application of carbon nanotubes as drug delivery carriers is stalled by uncertainties over their distribution and toxicity in vivo. Here, the authors use animal models to show that, while the bulk of nanotubes is renally cleared, a fraction can be eliminated through an alternative hepatobiliary pathway.
format	article
author	Simone Alidori Robert L. Bowman Dmitry Yarilin Yevgeniy Romin Afsar Barlas J. Justin Mulvey Sho Fujisawa Ke Xu Alessandro Ruggiero Vladimir Riabov Daniel L. J. Thorek Hans David S. Ulmert Elliott J. Brea Katja Behling Julia Kzhyshkowska Katia Manova-Todorova David A. Scheinberg Michael R. McDevitt
author_facet	Simone Alidori Robert L. Bowman Dmitry Yarilin Yevgeniy Romin Afsar Barlas J. Justin Mulvey Sho Fujisawa Ke Xu Alessandro Ruggiero Vladimir Riabov Daniel L. J. Thorek Hans David S. Ulmert Elliott J. Brea Katja Behling Julia Kzhyshkowska Katia Manova-Todorova David A. Scheinberg Michael R. McDevitt
author_sort	Simone Alidori
title	Deconvoluting hepatic processing of carbon nanotubes
title_short	Deconvoluting hepatic processing of carbon nanotubes
title_full	Deconvoluting hepatic processing of carbon nanotubes
title_fullStr	Deconvoluting hepatic processing of carbon nanotubes
title_full_unstemmed	Deconvoluting hepatic processing of carbon nanotubes
title_sort	deconvoluting hepatic processing of carbon nanotubes
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/423150c700094e65a6244050ab69116e
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_version_	1718382620687990784

Deconvoluting hepatic processing of carbon nanotubes

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