Molecular epidemiology and antimicrobials resistance mechanism of Mycoplasma genitlaium

Currently, infections caused by Mycoplasma genitalium are ones the most common sexually transmitted infections. Their prevalence is varied from 1.3% to 15.9%. Infections caused by M.genitalium may lead to urethritis in men and a wide spectrum of diseases in women. Antibiotic resistance now is one of...

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Autores principales:	Elizaveta Dmitrievna Shedko, Elena Nokolaevna Goloveshkina, Vasiliy Gennadievich Akimkin
Formato:	article
Lenguaje:	RU
Publicado:	State Scientific Center of Dermatovenereology and Cosmetology 2021
Materias:	mycoplasma genitalium antibiotic resistance 23s rrna qrdr molecular diagnostics Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/423b4322cad1426189a6ba69f9b4aff9
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spelling	oai:doaj.org-article:423b4322cad1426189a6ba69f9b4aff92021-12-01T22:16:30ZMolecular epidemiology and antimicrobials resistance mechanism of Mycoplasma genitlaium0042-46092313-629410.25208/vdv1192https://doaj.org/article/423b4322cad1426189a6ba69f9b4aff92021-07-01T00:00:00Zhttps://vestnikdv.ru/jour/article/viewFile/1192/1201https://doaj.org/toc/0042-4609https://doaj.org/toc/2313-6294Currently, infections caused by Mycoplasma genitalium are ones the most common sexually transmitted infections. Their prevalence is varied from 1.3% to 15.9%. Infections caused by M.genitalium may lead to urethritis in men and a wide spectrum of diseases in women. Antibiotic resistance now is one of the most emerging problems both in the scientific and in the healthcare fields. The usage of antimicrobials inhibiting cell wall synthesis for the treatment of M.genitalium is ineffective, and resistance to macrolides and fluoroquinolones is increasing rapidly. M.genitalium infections diagnostics is complicated due to specific conditions and duration of culture methods. The usage of nucleic acid amplification techniques is the most relevant for laboratory diagnostics, and is used in existing assays. This review compiles current data on the prevalence, molecular mechanisms of pathogenesis and antibiotic resistance, as well as diagnostics methods of M.genitalium.Elizaveta Dmitrievna ShedkoElena Nokolaevna GoloveshkinaVasiliy Gennadievich AkimkinState Scientific Center of Dermatovenereology and Cosmetologyarticlemycoplasma genitaliumantibiotic resistance23s rrnaqrdrmolecular diagnosticsDermatologyRL1-803RUVestnik Dermatologii i Venerologii, Vol 97, Iss 3, Pp 14-23 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	mycoplasma genitalium antibiotic resistance 23s rrna qrdr molecular diagnostics Dermatology RL1-803
spellingShingle	mycoplasma genitalium antibiotic resistance 23s rrna qrdr molecular diagnostics Dermatology RL1-803 Elizaveta Dmitrievna Shedko Elena Nokolaevna Goloveshkina Vasiliy Gennadievich Akimkin Molecular epidemiology and antimicrobials resistance mechanism of Mycoplasma genitlaium
description	Currently, infections caused by Mycoplasma genitalium are ones the most common sexually transmitted infections. Their prevalence is varied from 1.3% to 15.9%. Infections caused by M.genitalium may lead to urethritis in men and a wide spectrum of diseases in women. Antibiotic resistance now is one of the most emerging problems both in the scientific and in the healthcare fields. The usage of antimicrobials inhibiting cell wall synthesis for the treatment of M.genitalium is ineffective, and resistance to macrolides and fluoroquinolones is increasing rapidly. M.genitalium infections diagnostics is complicated due to specific conditions and duration of culture methods. The usage of nucleic acid amplification techniques is the most relevant for laboratory diagnostics, and is used in existing assays. This review compiles current data on the prevalence, molecular mechanisms of pathogenesis and antibiotic resistance, as well as diagnostics methods of M.genitalium.
format	article
author	Elizaveta Dmitrievna Shedko Elena Nokolaevna Goloveshkina Vasiliy Gennadievich Akimkin
author_facet	Elizaveta Dmitrievna Shedko Elena Nokolaevna Goloveshkina Vasiliy Gennadievich Akimkin
author_sort	Elizaveta Dmitrievna Shedko
title	Molecular epidemiology and antimicrobials resistance mechanism of Mycoplasma genitlaium
title_short	Molecular epidemiology and antimicrobials resistance mechanism of Mycoplasma genitlaium
title_full	Molecular epidemiology and antimicrobials resistance mechanism of Mycoplasma genitlaium
title_fullStr	Molecular epidemiology and antimicrobials resistance mechanism of Mycoplasma genitlaium
title_full_unstemmed	Molecular epidemiology and antimicrobials resistance mechanism of Mycoplasma genitlaium
title_sort	molecular epidemiology and antimicrobials resistance mechanism of mycoplasma genitlaium
publisher	State Scientific Center of Dermatovenereology and Cosmetology
publishDate	2021
url	https://doaj.org/article/423b4322cad1426189a6ba69f9b4aff9
work_keys_str_mv	AT elizavetadmitrievnashedko molecularepidemiologyandantimicrobialsresistancemechanismofmycoplasmagenitlaium AT elenanokolaevnagoloveshkina molecularepidemiologyandantimicrobialsresistancemechanismofmycoplasmagenitlaium AT vasiliygennadievichakimkin molecularepidemiologyandantimicrobialsresistancemechanismofmycoplasmagenitlaium
_version_	1718404156700491776

Molecular epidemiology and antimicrobials resistance mechanism of Mycoplasma genitlaium

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