TFEB Dependent Autophagy-Lysosomal Pathway: An Emerging Pharmacological Target in Sepsis
Sepsis is a life-threatening syndrome induced by aberrant host response towards infection. The autophagy-lysosomal pathway (ALP) plays a fundamental role in maintaining cellular homeostasis and conferring organ protection. However, this pathway is often impaired in sepsis, resulting in dysregulated...
Guardado en:
Autores principales: | Xin Liu, Xinchuan Zheng, Yongling Lu, Qian Chen, Jiang Zheng, Hong Zhou |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4243e40015c64570a4b6cf66797b8dee |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Translation Inhibitors Activate Autophagy Master Regulators TFEB and TFE3
por: Thao Thi Dang, et al.
Publicado: (2021) -
Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti-hypertension effect
por: Linhua Deng, et al.
Publicado: (2022) -
Intracellular Trafficking and Persistence of <named-content content-type="genus-species">Acinetobacter baumannii</named-content> Requires Transcription Factor EB
por: Raquel Parra-Millán, et al.
Publicado: (2018) -
Silica nanoparticles induce autophagy dysfunction via lysosomal impairment and inhibition of autophagosome degradation in hepatocytes
por: Wang J, et al.
Publicado: (2017) -
LRRK2 inhibitors and their potential in the treatment of Parkinson’s disease: current perspectives
por: Atashrazm F, et al.
Publicado: (2016)