Characterisation of Lamp2-deficient rats for potential new animal model of Danon disease

Abstract Danon disease (DD) is caused by the absence or malfunction of lysosomal-associated membrane protein 2 (LAMP2). Although Lamp2-deficient mice and DD patients have similar characteristics, these mice have clear limitations and are clinically inconsistent. The aim of our paper is to outline th...

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Autores principales: Shuoyi Ma, Miao Zhang, Shuai Zhang, Jing Wang, Xia Zhou, Guanya Guo, Lu Wang, Min Wang, Zhengwu Peng, Changcun Guo, Xiaohong Zheng, Xinmin Zhou, Jingbo Wang, Ying Han
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/42546d8a5af4421d9c104a2c696c869a
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