Systematic identification of protein combinations mediating chromatin looping

The formation of chromatin loops is mainly mediated by DNA-binding proteins (DBPs) that bind to the interacting sites and form complexes in 3D space. Here, Zhang et al.present an algorithm integrating ChIP-seq and Hi-C data to systematically identify both the 1D- and 3D-cooperation between DBPs.

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Detalles Bibliográficos
Autores principales:	Kai Zhang, Nan Li, Richard I. Ainsworth, Wei Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/425a3914f66e48128f69d3e4fc16c500
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id	oai:doaj.org-article:425a3914f66e48128f69d3e4fc16c500
record_format	dspace
spelling	oai:doaj.org-article:425a3914f66e48128f69d3e4fc16c5002021-12-02T15:35:25ZSystematic identification of protein combinations mediating chromatin looping10.1038/ncomms122492041-1723https://doaj.org/article/425a3914f66e48128f69d3e4fc16c5002016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12249https://doaj.org/toc/2041-1723The formation of chromatin loops is mainly mediated by DNA-binding proteins (DBPs) that bind to the interacting sites and form complexes in 3D space. Here, Zhang et al.present an algorithm integrating ChIP-seq and Hi-C data to systematically identify both the 1D- and 3D-cooperation between DBPs.Kai ZhangNan LiRichard I. AinsworthWei WangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kai Zhang Nan Li Richard I. Ainsworth Wei Wang Systematic identification of protein combinations mediating chromatin looping
description	The formation of chromatin loops is mainly mediated by DNA-binding proteins (DBPs) that bind to the interacting sites and form complexes in 3D space. Here, Zhang et al.present an algorithm integrating ChIP-seq and Hi-C data to systematically identify both the 1D- and 3D-cooperation between DBPs.
format	article
author	Kai Zhang Nan Li Richard I. Ainsworth Wei Wang
author_facet	Kai Zhang Nan Li Richard I. Ainsworth Wei Wang
author_sort	Kai Zhang
title	Systematic identification of protein combinations mediating chromatin looping
title_short	Systematic identification of protein combinations mediating chromatin looping
title_full	Systematic identification of protein combinations mediating chromatin looping
title_fullStr	Systematic identification of protein combinations mediating chromatin looping
title_full_unstemmed	Systematic identification of protein combinations mediating chromatin looping
title_sort	systematic identification of protein combinations mediating chromatin looping
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/425a3914f66e48128f69d3e4fc16c500
work_keys_str_mv	AT kaizhang systematicidentificationofproteincombinationsmediatingchromatinlooping AT nanli systematicidentificationofproteincombinationsmediatingchromatinlooping AT richardiainsworth systematicidentificationofproteincombinationsmediatingchromatinlooping AT weiwang systematicidentificationofproteincombinationsmediatingchromatinlooping
_version_	1718386527999885312

Systematic identification of protein combinations mediating chromatin looping

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