Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Glutamine can feed into the TCA cycle as a fuel for oxidative phosphorylation and thereby can affect metabolic pathways in lymphocytes. Yet here the authors show that glutamine serves predominantly as a signalling molecule that sustains cMyc expression to control NK cell metabolism and effector func...

Full description

Saved in:
Bibliographic Details
Main Authors: Róisín M. Loftus, Nadine Assmann, Nidhi Kedia-Mehta, Katie L. O’Brien, Arianne Garcia, Conor Gillespie, Jens L. Hukelmann, Peter J. Oefner, Angus I. Lamond, Clair M. Gardiner, Katja Dettmer, Doreen A. Cantrell, Linda V. Sinclair, David K. Finlay
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
Q
Online Access:https://doaj.org/article/428103db6a8c40348a0ae092d9d2a982
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items