PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.
Some Heliconiaceae family species, had demonstrated to be effective neutralizing partial or totally the lethal, indirect hemolytic, hemorrhagic, proteolytic, clotting, miotoxic and edema-forming activities from the Bothrops asper (mapaná equis) venom. This work evaluates two species of heliconias:...
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Universidad de Antioquia
2009
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oai:doaj.org-article:429dddb3ce164a6b9b022d012d4caa2e2021-11-19T04:15:24ZPRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.0121-40042145-2660https://doaj.org/article/429dddb3ce164a6b9b022d012d4caa2e2009-07-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/1938https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660Some Heliconiaceae family species, had demonstrated to be effective neutralizing partial or totally the lethal, indirect hemolytic, hemorrhagic, proteolytic, clotting, miotoxic and edema-forming activities from the Bothrops asper (mapaná equis) venom. This work evaluates two species of heliconias: Heliconia psittacorum and Heliconia rostrata against the indirect hemolytic, proteolytic and clotting activities induced by B. asper without any inhibitory effect on the indirect hemolytic and proteolytic effects. On the contrary, the extracts retard the venom clotting effect with regard to the positive control up to 45.59 seconds. In the electrophoretic profile a band belonging to the H. psittacorum is observed, moreover a decrease and increase in the intensity of some bands (66 y 31 KDa respectively) possibly indicate its degradation by the extracts. The phytochemical evaluation of the extracts shows the presence of primary metabolites as glucids and proteins; and secondary metabolites as phenolics compounds, terpenoides and cumarins, some of them reported in others vegetal species as responsible of the anti-ophidian activity. Sebastián ESTRADA G.Juan C. QUINTANASilvia L. JIMENÉSJuan C. Alarcón P.Jaime A. PEREAÑEZ J.Leidy J. VARGASUniversidad de AntioquiaarticleBothrops asperHeliconiaceaephenolic compoundscumarinsclotting activity.Food processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 16, Iss 2 (2009) |
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language |
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topic |
Bothrops asper Heliconiaceae phenolic compounds cumarins clotting activity. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 |
spellingShingle |
Bothrops asper Heliconiaceae phenolic compounds cumarins clotting activity. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Sebastián ESTRADA G. Juan C. QUINTANA Silvia L. JIMENÉS Juan C. Alarcón P. Jaime A. PEREAÑEZ J. Leidy J. VARGAS PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM. |
description |
Some Heliconiaceae family species, had demonstrated to be effective neutralizing partial or totally the lethal, indirect hemolytic, hemorrhagic, proteolytic, clotting, miotoxic and edema-forming activities from the Bothrops asper (mapaná equis) venom. This work evaluates two species of heliconias: Heliconia psittacorum and Heliconia rostrata against the indirect hemolytic, proteolytic and clotting activities induced by B. asper without any inhibitory effect on the indirect hemolytic and proteolytic effects. On the contrary, the extracts retard the venom clotting effect with regard to the positive control up to 45.59 seconds. In the electrophoretic profile a band belonging to the H. psittacorum is observed, moreover a decrease and increase in the intensity of some bands (66 y 31 KDa respectively) possibly indicate its degradation by the extracts. The phytochemical evaluation of the extracts shows the presence of primary metabolites as glucids and proteins; and secondary metabolites as phenolics compounds, terpenoides and cumarins, some of them reported in others vegetal species as responsible of the anti-ophidian activity.
|
format |
article |
author |
Sebastián ESTRADA G. Juan C. QUINTANA Silvia L. JIMENÉS Juan C. Alarcón P. Jaime A. PEREAÑEZ J. Leidy J. VARGAS |
author_facet |
Sebastián ESTRADA G. Juan C. QUINTANA Silvia L. JIMENÉS Juan C. Alarcón P. Jaime A. PEREAÑEZ J. Leidy J. VARGAS |
author_sort |
Sebastián ESTRADA G. |
title |
PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM. |
title_short |
PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM. |
title_full |
PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM. |
title_fullStr |
PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM. |
title_full_unstemmed |
PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM. |
title_sort |
preliminary phytochemistry assessment of <i> heliconia rostrata </i> and the potential inhibitory activity of some effects of the <i> bothrops asper </i> (mapanà x) venom. |
publisher |
Universidad de Antioquia |
publishDate |
2009 |
url |
https://doaj.org/article/429dddb3ce164a6b9b022d012d4caa2e |
work_keys_str_mv |
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