PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.

Some Heliconiaceae family species, had demonstrated to be effective neutralizing partial or totally the lethal, indirect hemolytic, hemorrhagic, proteolytic, clotting, miotoxic and edema-forming activities from the Bothrops asper (mapaná equis) venom. This work evaluates two species of heliconias:...

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Autores principales: Sebastián ESTRADA G., Juan C. QUINTANA, Silvia L. JIMENÉS, Juan C. Alarcón P., Jaime A. PEREAÑEZ J., Leidy J. VARGAS
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Publicado: Universidad de Antioquia 2009
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spelling oai:doaj.org-article:429dddb3ce164a6b9b022d012d4caa2e2021-11-19T04:15:24ZPRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.0121-40042145-2660https://doaj.org/article/429dddb3ce164a6b9b022d012d4caa2e2009-07-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/1938https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660Some Heliconiaceae family species, had demonstrated to be effective neutralizing partial or totally the lethal, indirect hemolytic, hemorrhagic, proteolytic, clotting, miotoxic and edema-forming activities from the Bothrops asper (mapaná equis) venom. This work evaluates two species of heliconias: Heliconia psittacorum and Heliconia rostrata  against the indirect hemolytic, proteolytic and clotting activities induced by B. asper without any inhibitory effect on the indirect hemolytic and proteolytic effects. On the contrary, the extracts retard the venom clotting effect with regard to the positive control up to 45.59 seconds. In the electrophoretic profile a band belonging to the H. psittacorum is observed, moreover a decrease and increase in the intensity of some bands (66 y 31 KDa respectively) possibly indicate its degradation by the extracts. The phytochemical evaluation of the extracts shows the presence of primary metabolites as glucids and proteins; and secondary metabolites as phenolics compounds, terpenoides and cumarins, some of them reported in others vegetal species as responsible of the anti-ophidian activity. Sebastián ESTRADA G.Juan C. QUINTANASilvia L. JIMENÉSJuan C. Alarcón P.Jaime A. PEREAÑEZ J.Leidy J. VARGASUniversidad de AntioquiaarticleBothrops asperHeliconiaceaephenolic compoundscumarinsclotting activity.Food processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 16, Iss 2 (2009)
institution DOAJ
collection DOAJ
language EN
topic Bothrops asper
Heliconiaceae
phenolic compounds
cumarins
clotting activity.
Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
spellingShingle Bothrops asper
Heliconiaceae
phenolic compounds
cumarins
clotting activity.
Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
Sebastián ESTRADA G.
Juan C. QUINTANA
Silvia L. JIMENÉS
Juan C. Alarcón P.
Jaime A. PEREAÑEZ J.
Leidy J. VARGAS
PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.
description Some Heliconiaceae family species, had demonstrated to be effective neutralizing partial or totally the lethal, indirect hemolytic, hemorrhagic, proteolytic, clotting, miotoxic and edema-forming activities from the Bothrops asper (mapaná equis) venom. This work evaluates two species of heliconias: Heliconia psittacorum and Heliconia rostrata  against the indirect hemolytic, proteolytic and clotting activities induced by B. asper without any inhibitory effect on the indirect hemolytic and proteolytic effects. On the contrary, the extracts retard the venom clotting effect with regard to the positive control up to 45.59 seconds. In the electrophoretic profile a band belonging to the H. psittacorum is observed, moreover a decrease and increase in the intensity of some bands (66 y 31 KDa respectively) possibly indicate its degradation by the extracts. The phytochemical evaluation of the extracts shows the presence of primary metabolites as glucids and proteins; and secondary metabolites as phenolics compounds, terpenoides and cumarins, some of them reported in others vegetal species as responsible of the anti-ophidian activity.
format article
author Sebastián ESTRADA G.
Juan C. QUINTANA
Silvia L. JIMENÉS
Juan C. Alarcón P.
Jaime A. PEREAÑEZ J.
Leidy J. VARGAS
author_facet Sebastián ESTRADA G.
Juan C. QUINTANA
Silvia L. JIMENÉS
Juan C. Alarcón P.
Jaime A. PEREAÑEZ J.
Leidy J. VARGAS
author_sort Sebastián ESTRADA G.
title PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.
title_short PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.
title_full PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.
title_fullStr PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.
title_full_unstemmed PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF <I> Heliconia rostrata </I> AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE <I> Bothrops asper </I> (mapanà X) VENOM.
title_sort preliminary phytochemistry assessment of <i> heliconia rostrata </i> and the potential inhibitory activity of some effects of the <i> bothrops asper </i> (mapanà x) venom.
publisher Universidad de Antioquia
publishDate 2009
url https://doaj.org/article/429dddb3ce164a6b9b022d012d4caa2e
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