The evolution of sex-specific virulence in infectious diseases
Many infectious diseases are more likely to progress to serious illness or death in men than in women, which has been attributed to a stronger immune response in women. Here, the authors propose that pathogen transmission from mother to child favours the evolution of lower virulence in women, and ar...
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Nature Portfolio
2016
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oai:doaj.org-article:42aa9621a6c74bfa9493dc923ef0d2aa2021-12-02T14:40:11ZThe evolution of sex-specific virulence in infectious diseases10.1038/ncomms138492041-1723https://doaj.org/article/42aa9621a6c74bfa9493dc923ef0d2aa2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13849https://doaj.org/toc/2041-1723Many infectious diseases are more likely to progress to serious illness or death in men than in women, which has been attributed to a stronger immune response in women. Here, the authors propose that pathogen transmission from mother to child favours the evolution of lower virulence in women, and argue that the higher risk of HTLV-1 infection progressing to leukaemia in Japanese men is due to prolonged breastfeeding in Japan.Francisco ÚbedaVincent A. A. JansenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
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Science Q Francisco Úbeda Vincent A. A. Jansen The evolution of sex-specific virulence in infectious diseases |
description |
Many infectious diseases are more likely to progress to serious illness or death in men than in women, which has been attributed to a stronger immune response in women. Here, the authors propose that pathogen transmission from mother to child favours the evolution of lower virulence in women, and argue that the higher risk of HTLV-1 infection progressing to leukaemia in Japanese men is due to prolonged breastfeeding in Japan. |
format |
article |
author |
Francisco Úbeda Vincent A. A. Jansen |
author_facet |
Francisco Úbeda Vincent A. A. Jansen |
author_sort |
Francisco Úbeda |
title |
The evolution of sex-specific virulence in infectious diseases |
title_short |
The evolution of sex-specific virulence in infectious diseases |
title_full |
The evolution of sex-specific virulence in infectious diseases |
title_fullStr |
The evolution of sex-specific virulence in infectious diseases |
title_full_unstemmed |
The evolution of sex-specific virulence in infectious diseases |
title_sort |
evolution of sex-specific virulence in infectious diseases |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/42aa9621a6c74bfa9493dc923ef0d2aa |
work_keys_str_mv |
AT franciscoubeda theevolutionofsexspecificvirulenceininfectiousdiseases AT vincentaajansen theevolutionofsexspecificvirulenceininfectiousdiseases AT franciscoubeda evolutionofsexspecificvirulenceininfectiousdiseases AT vincentaajansen evolutionofsexspecificvirulenceininfectiousdiseases |
_version_ |
1718390351758098432 |