The evolution of sex-specific virulence in infectious diseases

Many infectious diseases are more likely to progress to serious illness or death in men than in women, which has been attributed to a stronger immune response in women. Here, the authors propose that pathogen transmission from mother to child favours the evolution of lower virulence in women, and ar...

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Autores principales: Francisco Úbeda, Vincent A. A. Jansen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/42aa9621a6c74bfa9493dc923ef0d2aa
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spelling oai:doaj.org-article:42aa9621a6c74bfa9493dc923ef0d2aa2021-12-02T14:40:11ZThe evolution of sex-specific virulence in infectious diseases10.1038/ncomms138492041-1723https://doaj.org/article/42aa9621a6c74bfa9493dc923ef0d2aa2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13849https://doaj.org/toc/2041-1723Many infectious diseases are more likely to progress to serious illness or death in men than in women, which has been attributed to a stronger immune response in women. Here, the authors propose that pathogen transmission from mother to child favours the evolution of lower virulence in women, and argue that the higher risk of HTLV-1 infection progressing to leukaemia in Japanese men is due to prolonged breastfeeding in Japan.Francisco ÚbedaVincent A. A. JansenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Francisco Úbeda
Vincent A. A. Jansen
The evolution of sex-specific virulence in infectious diseases
description Many infectious diseases are more likely to progress to serious illness or death in men than in women, which has been attributed to a stronger immune response in women. Here, the authors propose that pathogen transmission from mother to child favours the evolution of lower virulence in women, and argue that the higher risk of HTLV-1 infection progressing to leukaemia in Japanese men is due to prolonged breastfeeding in Japan.
format article
author Francisco Úbeda
Vincent A. A. Jansen
author_facet Francisco Úbeda
Vincent A. A. Jansen
author_sort Francisco Úbeda
title The evolution of sex-specific virulence in infectious diseases
title_short The evolution of sex-specific virulence in infectious diseases
title_full The evolution of sex-specific virulence in infectious diseases
title_fullStr The evolution of sex-specific virulence in infectious diseases
title_full_unstemmed The evolution of sex-specific virulence in infectious diseases
title_sort evolution of sex-specific virulence in infectious diseases
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/42aa9621a6c74bfa9493dc923ef0d2aa
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