Phospholipase D2 loss results in increased blood pressure via inhibition of the endothelial nitric oxide synthase pathway

Abstract The Phospholipase D (PLD) superfamily is linked to neurological disease, cancer, and fertility, and a recent report correlated a potential loss-of-function PLD2 polymorphism with hypotension. Surprisingly, PLD2 −/− mice exhibit elevated blood pressure accompanied by associated changes in ca...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Rochelle K. Nelson, Jiang Ya-Ping, John Gadbery, Danya Abedeen, Nicole Sampson, Richard Z. Lin, Michael A. Frohman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
R
Q
Acceso en línea:https://doaj.org/article/42acf75c41c5480eb53ff6de77c917bc
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!