Angle change of the A-domain in a single SERCA1a molecule detected by defocused orientation imaging
Abstract The sarcoendoplasmic reticulum Ca2+-ATPase (SERCA) transports Ca2+ ions across the membrane coupled with ATP hydrolysis. Crystal structures of ligand-stabilized molecules indicate that the movement of actuator (A) domain plays a crucial role in Ca2+ translocation. However, the actual struct...
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Autores principales: | Takanobu A. Katoh, Takashi Daiho, Kazuo Yamasaki, Stefania Danko, Shoko Fujimura, Hiroshi Suzuki |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Acceso en línea: | https://doaj.org/article/42b4be887568440d87720bad745fb185 |
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