Monolithic Papain-Immobilized Enzyme Reactors for Automated Structural Characterization of Monoclonal Antibodies

The characterization of monoclonal antibodies (mAbs) requires laborious and time-consuming sample preparation steps before the liquid chromatography–mass spectrometry (LC-MS) analysis. Middle-up approaches entailing the use of specific proteases (papain, IdeS, etc.) emerged as practical and informat...

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Autores principales: Francesca Rinaldi, Sara Tengattini, Gloria Brusotti, Giuseppe Tripodo, Benjamin Peters, Caterina Temporini, Gabriella Massolini, Enrica Calleri
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/42c28a381a7749fe9825f9b785333003
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