Monolithic Papain-Immobilized Enzyme Reactors for Automated Structural Characterization of Monoclonal Antibodies
The characterization of monoclonal antibodies (mAbs) requires laborious and time-consuming sample preparation steps before the liquid chromatography–mass spectrometry (LC-MS) analysis. Middle-up approaches entailing the use of specific proteases (papain, IdeS, etc.) emerged as practical and informat...
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Autores principales: | Francesca Rinaldi, Sara Tengattini, Gloria Brusotti, Giuseppe Tripodo, Benjamin Peters, Caterina Temporini, Gabriella Massolini, Enrica Calleri |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/42c28a381a7749fe9825f9b785333003 |
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