Persistent hyperammonia and altered concentrations of urea cycle metabolites in a 5-day swine experiment of sepsis

Abstract We measured plasma and cerebrospinal fluid (CSF) metabolite concentrations in a 5-day porcine sepsis model of fecal peritonitis. The objectives were: (i) to verify whether the expected pathways that had emerged in previous studies pertain only to the early inflammatory response or persist f...

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Bibliographic Details
Main Authors: Manuela Ferrario, Roberta Pastorelli, Laura Brunelli, Shengchen Liu, Pedro Paulo Zanella do Amaral Campos, Daniela Casoni, Werner J. Z’Graggen, Stephan M. Jakob
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/42c83fff2d0f45b7b5c0834643ddebe8
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