Persistent hyperammonia and altered concentrations of urea cycle metabolites in a 5-day swine experiment of sepsis
Abstract We measured plasma and cerebrospinal fluid (CSF) metabolite concentrations in a 5-day porcine sepsis model of fecal peritonitis. The objectives were: (i) to verify whether the expected pathways that had emerged in previous studies pertain only to the early inflammatory response or persist f...
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Main Authors: | Manuela Ferrario, Roberta Pastorelli, Laura Brunelli, Shengchen Liu, Pedro Paulo Zanella do Amaral Campos, Daniela Casoni, Werner J. Z’Graggen, Stephan M. Jakob |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/42c83fff2d0f45b7b5c0834643ddebe8 |
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