Adjunctive use of celecoxib with anti-tuberculosis drugs: evaluation in a whole-blood bactericidal activity model

Abstract COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. We investigated celecoxib (a COX-2 inhibitor) alone a...

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Main Authors: Claire M. Naftalin, Rupangi Verma, Meera Gurumurthy, Kim Hor Hee, Qingshu Lu, Benjamin Chaik Meng Yeo, Kin Hup Tan, Wenwei Lin, Buduo Yu, Kok Yong Seng, Lawrence Soon-U Lee, Nicholas I. Paton
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/42cbd61d772947248c58c2e871ff77ab
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