Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment

Giuseppe Lo Giudice1, Valentina de Belvis2, Marco Tavolato1, Alessandro Galan11San Paolo Ophthalmic Center, San Antonio Hospital, Padova, Italy; 2Paediatric Low Vision Center, Paediatric Rare Eye Disease Center, Department of Paediatrics, University of Padova, ItalyPurpose: To report the effect of s...

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Autores principales:	Giuseppe Lo Giudice, Valentina de Belvis, Marco Tavolato, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/42cf541e77e441d9aa8ba5757536782d
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spelling	oai:doaj.org-article:42cf541e77e441d9aa8ba5757536782d2021-12-02T00:10:01ZLarge-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment1177-54671177-5483https://doaj.org/article/42cf541e77e441d9aa8ba5757536782d2011-03-01T00:00:00Zhttp://www.dovepress.com/large-spot-subthreshold-transpupillary-thermotherapy-for-chronic-serou-a6659https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Giuseppe Lo Giudice1, Valentina de Belvis2, Marco Tavolato1, Alessandro Galan11San Paolo Ophthalmic Center, San Antonio Hospital, Padova, Italy; 2Paediatric Low Vision Center, Paediatric Rare Eye Disease Center, Department of Paediatrics, University of Padova, ItalyPurpose: To report the effect of subthreshold transpupillary thermotherapy (TTT) in treating serous detachment of the neurosensory retina secondary to chronic central serous chorioretinopathy (CCSC).Methods: Seven eyes from five patients with CCSC, persistent serous detachment of the neurosensory retina and a clinical course of between 12 and 60 months were treated. All eyes received large-spot TTT guided by indocyanine green angiography (ICGA). Subthreshold TTT was performed using an 810 nm diode laser with a spot size of 3.0 mm (power was set at 350 mW). Treatment was applied for 60 seconds to the areas of choroidal hyperfluorescence on ICGA.Results: The mean number of TTT sessions was 1.4 &plusmn; 0.5. All eyes were followed up for at least 6 months (mean 9.6 &plusmn; 3.2 standard deviation; range 6&ndash;12 months). The mean logarithm of the minimum angle of resolution best-corrected visual acuity was significantly better compared with baseline. All TTT-treated eyes had stable or improved vision (P &lt; 0.001). Mean optical coherence tomography (OCT) central foveal thickness was significantly lower in all patients (P &lt; 0.001) compared with pretreatment OCT, with a reduction in subretinal fluid and resolution of serous detachment associated with anatomical fovea restoration. No patient had any treatment-related side effects.Conclusion: Modified subthreshold TTT appears to have a beneficial effect in treating patients with CCSC and persistent neurosensory detachment. The encouraging results and lack of visually significant complications suggest that further investigation is warranted.Keywords: central serous chorioretinopathy, indocyanine green angiography, neurosensory detachment, transpupillary thermotherapy Giuseppe Lo GiudiceValentina de BelvisMarco Tavolatoet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 355-360 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Giuseppe Lo Giudice Valentina de Belvis Marco Tavolato et al Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment
description	Giuseppe Lo Giudice1, Valentina de Belvis2, Marco Tavolato1, Alessandro Galan11San Paolo Ophthalmic Center, San Antonio Hospital, Padova, Italy; 2Paediatric Low Vision Center, Paediatric Rare Eye Disease Center, Department of Paediatrics, University of Padova, ItalyPurpose: To report the effect of subthreshold transpupillary thermotherapy (TTT) in treating serous detachment of the neurosensory retina secondary to chronic central serous chorioretinopathy (CCSC).Methods: Seven eyes from five patients with CCSC, persistent serous detachment of the neurosensory retina and a clinical course of between 12 and 60 months were treated. All eyes received large-spot TTT guided by indocyanine green angiography (ICGA). Subthreshold TTT was performed using an 810 nm diode laser with a spot size of 3.0 mm (power was set at 350 mW). Treatment was applied for 60 seconds to the areas of choroidal hyperfluorescence on ICGA.Results: The mean number of TTT sessions was 1.4 &plusmn; 0.5. All eyes were followed up for at least 6 months (mean 9.6 &plusmn; 3.2 standard deviation; range 6&ndash;12 months). The mean logarithm of the minimum angle of resolution best-corrected visual acuity was significantly better compared with baseline. All TTT-treated eyes had stable or improved vision (P &lt; 0.001). Mean optical coherence tomography (OCT) central foveal thickness was significantly lower in all patients (P &lt; 0.001) compared with pretreatment OCT, with a reduction in subretinal fluid and resolution of serous detachment associated with anatomical fovea restoration. No patient had any treatment-related side effects.Conclusion: Modified subthreshold TTT appears to have a beneficial effect in treating patients with CCSC and persistent neurosensory detachment. The encouraging results and lack of visually significant complications suggest that further investigation is warranted.Keywords: central serous chorioretinopathy, indocyanine green angiography, neurosensory detachment, transpupillary thermotherapy
format	article
author	Giuseppe Lo Giudice Valentina de Belvis Marco Tavolato et al
author_facet	Giuseppe Lo Giudice Valentina de Belvis Marco Tavolato et al
author_sort	Giuseppe Lo Giudice
title	Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment
title_short	Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment
title_full	Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment
title_fullStr	Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment
title_full_unstemmed	Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment
title_sort	large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/42cf541e77e441d9aa8ba5757536782d
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Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment

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