Synthetic oxoisoaporphine alkaloids: in vitro, in vivo and in silico assessment of antileishmanial activities.

Leishmaniasis is a growing health problem worldwide. As there are certain drawbacks with the drugs currently used to treat human leishmaniasis and resistance to these drugs is emerging, there is a need to develop novel antileishmanial compounds, among which isoquinoline alkaloids are promising candi...

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Autores principales: Eduardo Sobarzo-Sánchez, Pablo Bilbao-Ramos, Maria Dea-Ayuela, Humberto González-Díaz, Matilde Yañez, Eugenio Uriarte, Lourdes Santana, Victoria Martínez-Sernández, Francisco Bolás-Fernández, Florencio M Ubeira
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/42d02becc0354f0b84780b4c633d05c4
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