NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95

NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95

Long-term depression (LTD) of synaptic strength contributes to circuit remodeling, memory encoding and erasure. Here, the authors show that P2XR- and NMDAR-dependent LTD are associated with distinct and precise molecular modifications that lead to specific modification of synapse function.

Saved in:
Bibliographic Details
Main Authors: Benjamin Compans, Come Camus, Emmanouela Kallergi, Silvia Sposini, Magalie Martineau, Corey Butler, Adel Kechkar, Remco V. Klaassen, Natacha Retailleau, Terrence J. Sejnowski, August B. Smit, Jean-Baptiste Sibarita, Thomas M. Bartol, David Perrais, Vassiliki Nikoletopoulou, Daniel Choquet, Eric Hosy
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/42d7f0f08a7745138e490a7bf976a87f
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items