Applicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use
Kozue Oana,1,2 Michiko Kobayashi,1 Dai Yamaki,3 Tsukasa Sakurada,3 Noriyuki Nagano,1,2 Yoshiyuki Kawakami1,2 1Division of Infection Control and Microbiological Regulation, Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine, 2Division of Clinical Microbiology,...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2015
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/42debb56f9174b529149a2c822b0bee0 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:42debb56f9174b529149a2c822b0bee0 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:42debb56f9174b529149a2c822b0bee02021-12-02T03:03:56ZApplicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use1178-2013https://doaj.org/article/42debb56f9174b529149a2c822b0bee02015-08-01T00:00:00Zhttp://www.dovepress.com/applicability-assessment-of-ceramic-microbeads-coated-with-hydroxyapat-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Kozue Oana,1,2 Michiko Kobayashi,1 Dai Yamaki,3 Tsukasa Sakurada,3 Noriyuki Nagano,1,2 Yoshiyuki Kawakami1,2 1Division of Infection Control and Microbiological Regulation, Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine, 2Division of Clinical Microbiology, Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University School of Medicine, Matsumoto, 3Shinshu Ceramics Co., Ltd., Kiso, Nagano, Japan Abstract: Water environments appear to be the habitats of Legionella species. Legionellosis is considered as a preventable illness because bacterial reservoirs can be controlled and removed. Roof-harvested rainwater has attracted significant attention not only as a groundwater recharge but also as a potential alternative source of nonpotable water. We successfully developed ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ using the thermal spraying method. The ceramic microbeads were demonstrated to have bactericidal activities against not only Legionella but also coliform and heterotrophic bacteria. Immersing the ceramic microbeads in household rainwater storage tanks was demonstrated to yield the favorable eradication of Legionella organisms. Not only rapid-acting but also long-lasting bactericidal activities of the ceramic microbead were exhibited against Legionella pneumophila. However, time-dependent attenuation of the bactericidal activities against Legionella were also noted in the sustainability appraisal experiment. Therefore, the problems to be overcome surely remain in constantly managing the Legionella-pollution by means of immersing the ceramic microbeads. The results of our investigation apparently indicate that the earthplus™-coated ceramic microbeads would become the favorable tool for Legionella measures in household rainwater storage tanks, which may become the natural reservoir for Legionella species. Our investigation would justify further research and data collection to obtain more reliable procedures to microbiologically regulate the Legionella in rainwater storage tanks. Keywords: hydroxyapatite, silver, TiO2, earthplus™, ceramic, Legionella, eradication, rainwater storage tankOana KKobayashi MYamaki DSakurada TNagano NKawakami YDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2015, Iss default, Pp 4971-4979 (2015) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine (General) R5-920 |
| spellingShingle |
Medicine (General) R5-920 Oana K Kobayashi M Yamaki D Sakurada T Nagano N Kawakami Y Applicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use |
| description |
Kozue Oana,1,2 Michiko Kobayashi,1 Dai Yamaki,3 Tsukasa Sakurada,3 Noriyuki Nagano,1,2 Yoshiyuki Kawakami1,2 1Division of Infection Control and Microbiological Regulation, Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine, 2Division of Clinical Microbiology, Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University School of Medicine, Matsumoto, 3Shinshu Ceramics Co., Ltd., Kiso, Nagano, Japan Abstract: Water environments appear to be the habitats of Legionella species. Legionellosis is considered as a preventable illness because bacterial reservoirs can be controlled and removed. Roof-harvested rainwater has attracted significant attention not only as a groundwater recharge but also as a potential alternative source of nonpotable water. We successfully developed ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ using the thermal spraying method. The ceramic microbeads were demonstrated to have bactericidal activities against not only Legionella but also coliform and heterotrophic bacteria. Immersing the ceramic microbeads in household rainwater storage tanks was demonstrated to yield the favorable eradication of Legionella organisms. Not only rapid-acting but also long-lasting bactericidal activities of the ceramic microbead were exhibited against Legionella pneumophila. However, time-dependent attenuation of the bactericidal activities against Legionella were also noted in the sustainability appraisal experiment. Therefore, the problems to be overcome surely remain in constantly managing the Legionella-pollution by means of immersing the ceramic microbeads. The results of our investigation apparently indicate that the earthplus™-coated ceramic microbeads would become the favorable tool for Legionella measures in household rainwater storage tanks, which may become the natural reservoir for Legionella species. Our investigation would justify further research and data collection to obtain more reliable procedures to microbiologically regulate the Legionella in rainwater storage tanks. Keywords: hydroxyapatite, silver, TiO2, earthplus™, ceramic, Legionella, eradication, rainwater storage tank |
| format |
article |
| author |
Oana K Kobayashi M Yamaki D Sakurada T Nagano N Kawakami Y |
| author_facet |
Oana K Kobayashi M Yamaki D Sakurada T Nagano N Kawakami Y |
| author_sort |
Oana K |
| title |
Applicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use |
| title_short |
Applicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use |
| title_full |
Applicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use |
| title_fullStr |
Applicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use |
| title_full_unstemmed |
Applicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use |
| title_sort |
applicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of legionella in rainwater storage tanks for household use |
| publisher |
Dove Medical Press |
| publishDate |
2015 |
| url |
https://doaj.org/article/42debb56f9174b529149a2c822b0bee0 |
| work_keys_str_mv |
AT oanak applicabilityassessmentofceramicmicrobeadscoatedwithhydroxyapatitebindingsilvertitaniumdioxideceramiccompositeearthplustradetotheeradicationoflegionellainrainwaterstoragetanksforhouseholduse AT kobayashim applicabilityassessmentofceramicmicrobeadscoatedwithhydroxyapatitebindingsilvertitaniumdioxideceramiccompositeearthplustradetotheeradicationoflegionellainrainwaterstoragetanksforhouseholduse AT yamakid applicabilityassessmentofceramicmicrobeadscoatedwithhydroxyapatitebindingsilvertitaniumdioxideceramiccompositeearthplustradetotheeradicationoflegionellainrainwaterstoragetanksforhouseholduse AT sakuradat applicabilityassessmentofceramicmicrobeadscoatedwithhydroxyapatitebindingsilvertitaniumdioxideceramiccompositeearthplustradetotheeradicationoflegionellainrainwaterstoragetanksforhouseholduse AT naganon applicabilityassessmentofceramicmicrobeadscoatedwithhydroxyapatitebindingsilvertitaniumdioxideceramiccompositeearthplustradetotheeradicationoflegionellainrainwaterstoragetanksforhouseholduse AT kawakamiy applicabilityassessmentofceramicmicrobeadscoatedwithhydroxyapatitebindingsilvertitaniumdioxideceramiccompositeearthplustradetotheeradicationoflegionellainrainwaterstoragetanksforhouseholduse |
| _version_ |
1718401980350595072 |