Circulating p16-Positive and p16-Negative Tumor Cells Serve as Independent Prognostic Indicators of Survival in Patients with Head and Neck Squamous Cell Carcinomas

Circulating p16-Positive and p16-Negative Tumor Cells Serve as Independent Prognostic Indicators of Survival in Patients with Head and Neck Squamous Cell Carcinomas

Background: Decisions regarding the staging, prognosis, and treatment of patients with head and neck squamous cell carcinomas (HNSCCs) are made after determining their p16 expression levels and human papillomavirus (HPV) infection status. Methods: We investigated the prognostic roles of p16-positive...

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Main Authors: Pei-Hung Chang, Hung-Ming Wang, Yung-Chia Kuo, Li-Yu Lee, Chia-Jung Liao, Hsuan-Chih Kuo, Cheng-Lung Hsu, Chun-Ta Liao, Sanger Hung-Chi Lin, Pei-Wei Huang, Tyler Min-Hsien Wu, Jason Chia-Hsun Hsieh
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
circulating tumor cells
p16 expression
head and neck squamous cell carcinoma
HPV genotyping
biomarker
liquid biopsy
Medicine
R
Online Access:https://doaj.org/article/42e37b72e2c544d787bb5a3b2475e529
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https://doaj.org/article/42e37b72e2c544d787bb5a3b2475e529

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