O-GlcNAcylation is required for B cell homeostasis and antibody responses

Post-translational modification has a variety of regulatory functions for important immune molecules. Here the authors use B-cell specific knockout mice to show how O-GlcNAcylation is required for functional B cell responses and humoral immunity.

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Autores principales:	Jung-Lin Wu, Ming-Feng Chiang, Pan-Hung Hsu, Dong-Yen Tsai, Kuo-Hsuan Hung, Ying-Hsiu Wang, Takashi Angata, Kuo-I Lin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/42e579fada414e81a85a98ec81b1f4d7
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spelling	oai:doaj.org-article:42e579fada414e81a85a98ec81b1f4d72021-12-02T15:38:53ZO-GlcNAcylation is required for B cell homeostasis and antibody responses10.1038/s41467-017-01677-z2041-1723https://doaj.org/article/42e579fada414e81a85a98ec81b1f4d72017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01677-zhttps://doaj.org/toc/2041-1723Post-translational modification has a variety of regulatory functions for important immune molecules. Here the authors use B-cell specific knockout mice to show how O-GlcNAcylation is required for functional B cell responses and humoral immunity.Jung-Lin WuMing-Feng ChiangPan-Hung HsuDong-Yen TsaiKuo-Hsuan HungYing-Hsiu WangTakashi AngataKuo-I LinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jung-Lin Wu Ming-Feng Chiang Pan-Hung Hsu Dong-Yen Tsai Kuo-Hsuan Hung Ying-Hsiu Wang Takashi Angata Kuo-I Lin O-GlcNAcylation is required for B cell homeostasis and antibody responses
description	Post-translational modification has a variety of regulatory functions for important immune molecules. Here the authors use B-cell specific knockout mice to show how O-GlcNAcylation is required for functional B cell responses and humoral immunity.
format	article
author	Jung-Lin Wu Ming-Feng Chiang Pan-Hung Hsu Dong-Yen Tsai Kuo-Hsuan Hung Ying-Hsiu Wang Takashi Angata Kuo-I Lin
author_facet	Jung-Lin Wu Ming-Feng Chiang Pan-Hung Hsu Dong-Yen Tsai Kuo-Hsuan Hung Ying-Hsiu Wang Takashi Angata Kuo-I Lin
author_sort	Jung-Lin Wu
title	O-GlcNAcylation is required for B cell homeostasis and antibody responses
title_short	O-GlcNAcylation is required for B cell homeostasis and antibody responses
title_full	O-GlcNAcylation is required for B cell homeostasis and antibody responses
title_fullStr	O-GlcNAcylation is required for B cell homeostasis and antibody responses
title_full_unstemmed	O-GlcNAcylation is required for B cell homeostasis and antibody responses
title_sort	o-glcnacylation is required for b cell homeostasis and antibody responses
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/42e579fada414e81a85a98ec81b1f4d7
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O-GlcNAcylation is required for B cell homeostasis and antibody responses

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