Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like

Stereocilia of the inner ear have graded heights that are thought to be regulated by the myosin-III family members MYO3A and MYO3B. Here the authors identify espin-1 and espin-like (ESPNL) as cargo that differentially influence the functions of both motors to regulate stereocilia length.

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Autores principales:	Seham Ebrahim, Matthew R. Avenarius, M’hamed Grati, Jocelyn F. Krey, Alanna M. Windsor, Aurea D. Sousa, Angela Ballesteros, Runjia Cui, Bryan A. Millis, Felipe T. Salles, Michelle A. Baird, Michael W. Davidson, Sherri M. Jones, Dongseok Choi, Lijin Dong, Manmeet H. Raval, Christopher M. Yengo, Peter G. Barr-Gillespie, Bechara Kachar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/42f55193d572437c9f31dff7d2836595
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spelling	oai:doaj.org-article:42f55193d572437c9f31dff7d28365952021-12-02T17:32:37ZStereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like10.1038/ncomms108332041-1723https://doaj.org/article/42f55193d572437c9f31dff7d28365952016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10833https://doaj.org/toc/2041-1723Stereocilia of the inner ear have graded heights that are thought to be regulated by the myosin-III family members MYO3A and MYO3B. Here the authors identify espin-1 and espin-like (ESPNL) as cargo that differentially influence the functions of both motors to regulate stereocilia length.Seham EbrahimMatthew R. AvenariusM’hamed GratiJocelyn F. KreyAlanna M. WindsorAurea D. SousaAngela BallesterosRunjia CuiBryan A. MillisFelipe T. SallesMichelle A. BairdMichael W. DavidsonSherri M. JonesDongseok ChoiLijin DongManmeet H. RavalChristopher M. YengoPeter G. Barr-GillespieBechara KacharNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Seham Ebrahim Matthew R. Avenarius M’hamed Grati Jocelyn F. Krey Alanna M. Windsor Aurea D. Sousa Angela Ballesteros Runjia Cui Bryan A. Millis Felipe T. Salles Michelle A. Baird Michael W. Davidson Sherri M. Jones Dongseok Choi Lijin Dong Manmeet H. Raval Christopher M. Yengo Peter G. Barr-Gillespie Bechara Kachar Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
description	Stereocilia of the inner ear have graded heights that are thought to be regulated by the myosin-III family members MYO3A and MYO3B. Here the authors identify espin-1 and espin-like (ESPNL) as cargo that differentially influence the functions of both motors to regulate stereocilia length.
format	article
author	Seham Ebrahim Matthew R. Avenarius M’hamed Grati Jocelyn F. Krey Alanna M. Windsor Aurea D. Sousa Angela Ballesteros Runjia Cui Bryan A. Millis Felipe T. Salles Michelle A. Baird Michael W. Davidson Sherri M. Jones Dongseok Choi Lijin Dong Manmeet H. Raval Christopher M. Yengo Peter G. Barr-Gillespie Bechara Kachar
author_facet	Seham Ebrahim Matthew R. Avenarius M’hamed Grati Jocelyn F. Krey Alanna M. Windsor Aurea D. Sousa Angela Ballesteros Runjia Cui Bryan A. Millis Felipe T. Salles Michelle A. Baird Michael W. Davidson Sherri M. Jones Dongseok Choi Lijin Dong Manmeet H. Raval Christopher M. Yengo Peter G. Barr-Gillespie Bechara Kachar
author_sort	Seham Ebrahim
title	Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
title_short	Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
title_full	Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
title_fullStr	Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
title_full_unstemmed	Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
title_sort	stereocilia-staircase spacing is influenced by myosin iii motors and their cargos espin-1 and espin-like
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/42f55193d572437c9f31dff7d2836595
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Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like

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