Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis
How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse sternum, which defines the relative dimensions of th...
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Nature Portfolio
2016
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oai:doaj.org-article:42f7f6edb5294acea1a1e36a07bb28792021-12-02T16:50:13ZDchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis10.1038/ncomms114692041-1723https://doaj.org/article/42f7f6edb5294acea1a1e36a07bb28792016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11469https://doaj.org/toc/2041-1723How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse sternum, which defines the relative dimensions of the sternum.Yaopan MaoAnna KutaIvan Crespo-EnriquezDanielle WhitingTina MartinJoanna MulvaneyKenneth D. IrvinePhilippa Francis-WestNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
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Science Q Yaopan Mao Anna Kuta Ivan Crespo-Enriquez Danielle Whiting Tina Martin Joanna Mulvaney Kenneth D. Irvine Philippa Francis-West Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis |
description |
How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse sternum, which defines the relative dimensions of the sternum. |
format |
article |
author |
Yaopan Mao Anna Kuta Ivan Crespo-Enriquez Danielle Whiting Tina Martin Joanna Mulvaney Kenneth D. Irvine Philippa Francis-West |
author_facet |
Yaopan Mao Anna Kuta Ivan Crespo-Enriquez Danielle Whiting Tina Martin Joanna Mulvaney Kenneth D. Irvine Philippa Francis-West |
author_sort |
Yaopan Mao |
title |
Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis |
title_short |
Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis |
title_full |
Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis |
title_fullStr |
Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis |
title_full_unstemmed |
Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis |
title_sort |
dchs1–fat4 regulation of polarized cell behaviours during skeletal morphogenesis |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/42f7f6edb5294acea1a1e36a07bb2879 |
work_keys_str_mv |
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1718383094806872064 |