Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis

How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse sternum, which defines the relative dimensions of th...

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Autores principales: Yaopan Mao, Anna Kuta, Ivan Crespo-Enriquez, Danielle Whiting, Tina Martin, Joanna Mulvaney, Kenneth D. Irvine, Philippa Francis-West
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/42f7f6edb5294acea1a1e36a07bb2879
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spelling oai:doaj.org-article:42f7f6edb5294acea1a1e36a07bb28792021-12-02T16:50:13ZDchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis10.1038/ncomms114692041-1723https://doaj.org/article/42f7f6edb5294acea1a1e36a07bb28792016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11469https://doaj.org/toc/2041-1723How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse sternum, which defines the relative dimensions of the sternum.Yaopan MaoAnna KutaIvan Crespo-EnriquezDanielle WhitingTina MartinJoanna MulvaneyKenneth D. IrvinePhilippa Francis-WestNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yaopan Mao
Anna Kuta
Ivan Crespo-Enriquez
Danielle Whiting
Tina Martin
Joanna Mulvaney
Kenneth D. Irvine
Philippa Francis-West
Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis
description How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse sternum, which defines the relative dimensions of the sternum.
format article
author Yaopan Mao
Anna Kuta
Ivan Crespo-Enriquez
Danielle Whiting
Tina Martin
Joanna Mulvaney
Kenneth D. Irvine
Philippa Francis-West
author_facet Yaopan Mao
Anna Kuta
Ivan Crespo-Enriquez
Danielle Whiting
Tina Martin
Joanna Mulvaney
Kenneth D. Irvine
Philippa Francis-West
author_sort Yaopan Mao
title Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis
title_short Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis
title_full Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis
title_fullStr Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis
title_full_unstemmed Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis
title_sort dchs1–fat4 regulation of polarized cell behaviours during skeletal morphogenesis
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/42f7f6edb5294acea1a1e36a07bb2879
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