Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis

How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse sternum, which defines the relative dimensions of th...

Full description

Saved in:
Bibliographic Details
Main Authors: Yaopan Mao, Anna Kuta, Ivan Crespo-Enriquez, Danielle Whiting, Tina Martin, Joanna Mulvaney, Kenneth D. Irvine, Philippa Francis-West
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/42f7f6edb5294acea1a1e36a07bb2879
Tags: Add Tag
No Tags, Be the first to tag this record!