Comparative survey of the relative impact of mRNA features on local ribosome profiling read density

Ribosome profiling data can suffer from uneven coverage which hampers estimation of elongation rates. Connor et al.present an enhanced data smoothing method for Ribo-seq data and highlight significant variability in sequence determinants of ribosome density in publicly available data sets.

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Autores principales: Patrick B. F. O’Connor, Dmitry E. Andreev, Pavel V. Baranov
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/42f88ac9182b471484c206f16074bb5e
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spelling oai:doaj.org-article:42f88ac9182b471484c206f16074bb5e2021-12-02T16:56:46ZComparative survey of the relative impact of mRNA features on local ribosome profiling read density10.1038/ncomms129152041-1723https://doaj.org/article/42f88ac9182b471484c206f16074bb5e2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12915https://doaj.org/toc/2041-1723Ribosome profiling data can suffer from uneven coverage which hampers estimation of elongation rates. Connor et al.present an enhanced data smoothing method for Ribo-seq data and highlight significant variability in sequence determinants of ribosome density in publicly available data sets.Patrick B. F. O’ConnorDmitry E. AndreevPavel V. BaranovNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Patrick B. F. O’Connor
Dmitry E. Andreev
Pavel V. Baranov
Comparative survey of the relative impact of mRNA features on local ribosome profiling read density
description Ribosome profiling data can suffer from uneven coverage which hampers estimation of elongation rates. Connor et al.present an enhanced data smoothing method for Ribo-seq data and highlight significant variability in sequence determinants of ribosome density in publicly available data sets.
format article
author Patrick B. F. O’Connor
Dmitry E. Andreev
Pavel V. Baranov
author_facet Patrick B. F. O’Connor
Dmitry E. Andreev
Pavel V. Baranov
author_sort Patrick B. F. O’Connor
title Comparative survey of the relative impact of mRNA features on local ribosome profiling read density
title_short Comparative survey of the relative impact of mRNA features on local ribosome profiling read density
title_full Comparative survey of the relative impact of mRNA features on local ribosome profiling read density
title_fullStr Comparative survey of the relative impact of mRNA features on local ribosome profiling read density
title_full_unstemmed Comparative survey of the relative impact of mRNA features on local ribosome profiling read density
title_sort comparative survey of the relative impact of mrna features on local ribosome profiling read density
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/42f88ac9182b471484c206f16074bb5e
work_keys_str_mv AT patrickbfoconnor comparativesurveyoftherelativeimpactofmrnafeaturesonlocalribosomeprofilingreaddensity
AT dmitryeandreev comparativesurveyoftherelativeimpactofmrnafeaturesonlocalribosomeprofilingreaddensity
AT pavelvbaranov comparativesurveyoftherelativeimpactofmrnafeaturesonlocalribosomeprofilingreaddensity
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