Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin

Abstract The spiny mouse (Acomys species) has emerged as an exciting research organism due to its remarkable ability to undergo scarless regeneration of skin wounds and ear punches. Excitingly, Acomys species demonstrate scar-free healing in a wide-range of tissues beyond the skin. In this perspecti...

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Autores principales:	Janak Gaire, Justin A. Varholick, Sabhya Rana, Michael D. Sunshine, Sylvain Doré, W. Brad Barbazuk, David D. Fuller, Malcolm Maden, Chelsey S. Simmons
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/4306fc73e62c49328f78cf0387d70821
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spelling	oai:doaj.org-article:4306fc73e62c49328f78cf0387d708212021-12-02T14:24:00ZSpiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin10.1038/s41536-020-00111-12057-3995https://doaj.org/article/4306fc73e62c49328f78cf0387d708212021-01-01T00:00:00Zhttps://doi.org/10.1038/s41536-020-00111-1https://doaj.org/toc/2057-3995Abstract The spiny mouse (Acomys species) has emerged as an exciting research organism due to its remarkable ability to undergo scarless regeneration of skin wounds and ear punches. Excitingly, Acomys species demonstrate scar-free healing in a wide-range of tissues beyond the skin. In this perspective article, we discuss published findings from a variety of tissues to highlight how this emerging research organism could shed light on numerous clinically relevant human diseases. We also discuss the challenges of working with this emerging research organism and suggest strategies for future Acomys-inspired research.Janak GaireJustin A. VarholickSabhya RanaMichael D. SunshineSylvain DoréW. Brad BarbazukDavid D. FullerMalcolm MadenChelsey S. SimmonsNature PortfolioarticleMedicineRENnpj Regenerative Medicine, Vol 6, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Janak Gaire Justin A. Varholick Sabhya Rana Michael D. Sunshine Sylvain Doré W. Brad Barbazuk David D. Fuller Malcolm Maden Chelsey S. Simmons Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin
description	Abstract The spiny mouse (Acomys species) has emerged as an exciting research organism due to its remarkable ability to undergo scarless regeneration of skin wounds and ear punches. Excitingly, Acomys species demonstrate scar-free healing in a wide-range of tissues beyond the skin. In this perspective article, we discuss published findings from a variety of tissues to highlight how this emerging research organism could shed light on numerous clinically relevant human diseases. We also discuss the challenges of working with this emerging research organism and suggest strategies for future Acomys-inspired research.
format	article
author	Janak Gaire Justin A. Varholick Sabhya Rana Michael D. Sunshine Sylvain Doré W. Brad Barbazuk David D. Fuller Malcolm Maden Chelsey S. Simmons
author_facet	Janak Gaire Justin A. Varholick Sabhya Rana Michael D. Sunshine Sylvain Doré W. Brad Barbazuk David D. Fuller Malcolm Maden Chelsey S. Simmons
author_sort	Janak Gaire
title	Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin
title_short	Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin
title_full	Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin
title_fullStr	Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin
title_full_unstemmed	Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin
title_sort	spiny mouse (acomys): an emerging research organism for regenerative medicine with applications beyond the skin
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4306fc73e62c49328f78cf0387d70821
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Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin

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