New Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients

The treatment of locally advanced esophageal squamous cell carcinoma is still controversial. Although, preoperative chemoradiation, followed by esophagectomy is the standard treatment, morbidity and patients’ quality of life problems after an esophagectomy are still considerable. Since a good pathol...

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Autores principales:	Tatcha Rerkrak, Somkiat Sunpaweravong
Formato:	article
Lenguaje:	EN
Publicado:	Prince of Songkla University 2021
Materias:	chemotherapy esophageal cancer radiation squamous cell carcinoma surgery Medicine R
Acceso en línea:	https://doaj.org/article/4312a3322fa0432ba6200e9136bac999
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spelling	oai:doaj.org-article:4312a3322fa0432ba6200e9136bac9992021-11-25T08:25:12ZNew Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients2586-99812630-055910.31584/jhsmr.2021817https://doaj.org/article/4312a3322fa0432ba6200e9136bac9992021-11-01T00:00:00Zhttps://www.jhsmr.org/index.php/jhsmr/article/view/817https://doaj.org/toc/2586-9981https://doaj.org/toc/2630-0559The treatment of locally advanced esophageal squamous cell carcinoma is still controversial. Although, preoperative chemoradiation, followed by esophagectomy is the standard treatment, morbidity and patients’ quality of life problems after an esophagectomy are still considerable. Since a good pathologic complete response rate in patients after preoperative chemoradiation, a wait and see policy (with active surveillance) has been introduced as a new alternative approach after chemoradiation. Active surveillance involves imaging and biopsy evaluations in patients after chemoradiation to detect residual or recurrent tumors. If there are no residual tumors, observation is considered. Surgery is reserved for patients who present with residual tumors or locoregional recurrence after surveillance to achieve complete resection (salvage esophagectomy). Based on evidence from recent studies, surveillance with salvage esophagectomy is a treatment option for locally advanced esophageal squamous cell carcinoma patients achieving a clinical complete response after chemoradiation.Tatcha RerkrakSomkiat SunpaweravongPrince of Songkla Universityarticlechemotherapyesophageal cancerradiationsquamous cell carcinomasurgeryMedicineRENJournal of Health Science and Medical Research (JHSMR), Vol 40, Iss 1, Pp 111-116 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chemotherapy esophageal cancer radiation squamous cell carcinoma surgery Medicine R
spellingShingle	chemotherapy esophageal cancer radiation squamous cell carcinoma surgery Medicine R Tatcha Rerkrak Somkiat Sunpaweravong New Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients
description	The treatment of locally advanced esophageal squamous cell carcinoma is still controversial. Although, preoperative chemoradiation, followed by esophagectomy is the standard treatment, morbidity and patients’ quality of life problems after an esophagectomy are still considerable. Since a good pathologic complete response rate in patients after preoperative chemoradiation, a wait and see policy (with active surveillance) has been introduced as a new alternative approach after chemoradiation. Active surveillance involves imaging and biopsy evaluations in patients after chemoradiation to detect residual or recurrent tumors. If there are no residual tumors, observation is considered. Surgery is reserved for patients who present with residual tumors or locoregional recurrence after surveillance to achieve complete resection (salvage esophagectomy). Based on evidence from recent studies, surveillance with salvage esophagectomy is a treatment option for locally advanced esophageal squamous cell carcinoma patients achieving a clinical complete response after chemoradiation.
format	article
author	Tatcha Rerkrak Somkiat Sunpaweravong
author_facet	Tatcha Rerkrak Somkiat Sunpaweravong
author_sort	Tatcha Rerkrak
title	New Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients
title_short	New Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients
title_full	New Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients
title_fullStr	New Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients
title_full_unstemmed	New Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients
title_sort	new trend of surgery in locally advanced esophageal squamous cell carcinoma patients
publisher	Prince of Songkla University
publishDate	2021
url	https://doaj.org/article/4312a3322fa0432ba6200e9136bac999
work_keys_str_mv	AT tatcharerkrak newtrendofsurgeryinlocallyadvancedesophagealsquamouscellcarcinomapatients AT somkiatsunpaweravong newtrendofsurgeryinlocallyadvancedesophagealsquamouscellcarcinomapatients
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New Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients

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