Comprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period

Abstract Introduction Prognostic situations differ in patients with malignant intracranial tumors. We focused on the quality of life, ability of daily living, and cognitive function of patients in the perisurgery period and investigated the correlation between them and the prognosis of patients. Mat...

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Autores principales:	Yaning Wang, Wenlin Chen, Tianrui Yang, Binghao Zhao, Lizhou Zhou, Ziren Kong, Yuekun Wang, Congxin Dai, Yu Wang, Wenbin Ma
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	brain metastases Cognitive assessment glioma malignant intracranial tumor quality of life Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/4315bef87e244358ad44376953da5ed4
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spelling	oai:doaj.org-article:4315bef87e244358ad44376953da5ed42021-11-25T06:06:36ZComprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period2162-327910.1002/brb3.2192https://doaj.org/article/4315bef87e244358ad44376953da5ed42021-11-01T00:00:00Zhttps://doi.org/10.1002/brb3.2192https://doaj.org/toc/2162-3279Abstract Introduction Prognostic situations differ in patients with malignant intracranial tumors. We focused on the quality of life, ability of daily living, and cognitive function of patients in the perisurgery period and investigated the correlation between them and the prognosis of patients. Materials and Methods Patients with malignant intracranial tumors admitted to Peking Union Medical College Hospital from May 2018 to August 2020 for surgery were included. The evaluations were performed 6 times in the perisurgery period. The questionnaires for assessment included QLQ‐C30, ADL, and so forth. Results A total of 165 patients were included (115 glioma and 50 brain metastases). Patients had their worst performance at the 7‐day postsurgical assessment (EORTC QLQ‐C30, ADL, HAD‐D, Frail Scale, MMSE, MoCA, CSHA‐FI, and NANO) and recovered at the 1‐month postsurgical assessment (p < .05). Patients with left‐sided tumors had signiﬁcantly worse cognitive function than patients with right‐sided tumors before surgery and at 7 days, 1 month, and 6 months after surgery (p < .05). The scores of QLQ‐C30 and QLQ‐BN20 at 1 month, 3 months, 6 months, and 1 year after surgery were used to reflect the prognosis, and the preoperative MoCA, NANO, CCI, CSHA‐FI, and HAD score might predict the quality of life and nutrition status after operation. Conclusion The quality of life and daily living ability of patients with malignant intracranial tumors decreased significantly 7 days after the surgery but recovered 1 month after the surgery. Patients with left hemisphere lesions had a worse cognitive function, while the ADL is associated with short‐term prognosis. The comprehensive evaluation of the perisurgical period can indicate the prognosis of patients and further guide clinical decision‐making.Yaning WangWenlin ChenTianrui YangBinghao ZhaoLizhou ZhouZiren KongYuekun WangCongxin DaiYu WangWenbin MaWileyarticlebrain metastasesCognitive assessmentgliomamalignant intracranial tumorquality of lifeNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENBrain and Behavior, Vol 11, Iss 11, Pp n/a-n/a (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	brain metastases Cognitive assessment glioma malignant intracranial tumor quality of life Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	brain metastases Cognitive assessment glioma malignant intracranial tumor quality of life Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Yaning Wang Wenlin Chen Tianrui Yang Binghao Zhao Lizhou Zhou Ziren Kong Yuekun Wang Congxin Dai Yu Wang Wenbin Ma Comprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period
description	Abstract Introduction Prognostic situations differ in patients with malignant intracranial tumors. We focused on the quality of life, ability of daily living, and cognitive function of patients in the perisurgery period and investigated the correlation between them and the prognosis of patients. Materials and Methods Patients with malignant intracranial tumors admitted to Peking Union Medical College Hospital from May 2018 to August 2020 for surgery were included. The evaluations were performed 6 times in the perisurgery period. The questionnaires for assessment included QLQ‐C30, ADL, and so forth. Results A total of 165 patients were included (115 glioma and 50 brain metastases). Patients had their worst performance at the 7‐day postsurgical assessment (EORTC QLQ‐C30, ADL, HAD‐D, Frail Scale, MMSE, MoCA, CSHA‐FI, and NANO) and recovered at the 1‐month postsurgical assessment (p < .05). Patients with left‐sided tumors had signiﬁcantly worse cognitive function than patients with right‐sided tumors before surgery and at 7 days, 1 month, and 6 months after surgery (p < .05). The scores of QLQ‐C30 and QLQ‐BN20 at 1 month, 3 months, 6 months, and 1 year after surgery were used to reflect the prognosis, and the preoperative MoCA, NANO, CCI, CSHA‐FI, and HAD score might predict the quality of life and nutrition status after operation. Conclusion The quality of life and daily living ability of patients with malignant intracranial tumors decreased significantly 7 days after the surgery but recovered 1 month after the surgery. Patients with left hemisphere lesions had a worse cognitive function, while the ADL is associated with short‐term prognosis. The comprehensive evaluation of the perisurgical period can indicate the prognosis of patients and further guide clinical decision‐making.
format	article
author	Yaning Wang Wenlin Chen Tianrui Yang Binghao Zhao Lizhou Zhou Ziren Kong Yuekun Wang Congxin Dai Yu Wang Wenbin Ma
author_facet	Yaning Wang Wenlin Chen Tianrui Yang Binghao Zhao Lizhou Zhou Ziren Kong Yuekun Wang Congxin Dai Yu Wang Wenbin Ma
author_sort	Yaning Wang
title	Comprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period
title_short	Comprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period
title_full	Comprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period
title_fullStr	Comprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period
title_full_unstemmed	Comprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period
title_sort	comprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/4315bef87e244358ad44376953da5ed4
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Comprehensive ability evaluation and trend analysis of patients with malignant intracranial tumors in the perisurgery period

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