Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
Following DNA damage, different processes come to action to aid repair. The authors here find that microtubule filaments within the cell nucleus capture and non-randomly mobilize damaged chromatin to mediate DNA repair.
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Nature Portfolio
2018
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oai:doaj.org-article:4320e998628b46a9b1f9a18feb648d852021-12-02T15:33:43ZNuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair10.1038/s41467-018-05009-72041-1723https://doaj.org/article/4320e998628b46a9b1f9a18feb648d852018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05009-7https://doaj.org/toc/2041-1723Following DNA damage, different processes come to action to aid repair. The authors here find that microtubule filaments within the cell nucleus capture and non-randomly mobilize damaged chromatin to mediate DNA repair.Roxanne OshidariJonathan StreckerDaniel K. C. ChungKaran J. AbrahamJanet N. Y. ChanChristopher J. DamarenKarim MekhailNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Roxanne Oshidari Jonathan Strecker Daniel K. C. Chung Karan J. Abraham Janet N. Y. Chan Christopher J. Damaren Karim Mekhail Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair |
description |
Following DNA damage, different processes come to action to aid repair. The authors here find that microtubule filaments within the cell nucleus capture and non-randomly mobilize damaged chromatin to mediate DNA repair. |
format |
article |
author |
Roxanne Oshidari Jonathan Strecker Daniel K. C. Chung Karan J. Abraham Janet N. Y. Chan Christopher J. Damaren Karim Mekhail |
author_facet |
Roxanne Oshidari Jonathan Strecker Daniel K. C. Chung Karan J. Abraham Janet N. Y. Chan Christopher J. Damaren Karim Mekhail |
author_sort |
Roxanne Oshidari |
title |
Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair |
title_short |
Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair |
title_full |
Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair |
title_fullStr |
Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair |
title_full_unstemmed |
Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair |
title_sort |
nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote dna repair |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/4320e998628b46a9b1f9a18feb648d85 |
work_keys_str_mv |
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_version_ |
1718387019842846720 |