Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair

Following DNA damage, different processes come to action to aid repair. The authors here find that microtubule filaments within the cell nucleus capture and non-randomly mobilize damaged chromatin to mediate DNA repair.

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Autores principales: Roxanne Oshidari, Jonathan Strecker, Daniel K. C. Chung, Karan J. Abraham, Janet N. Y. Chan, Christopher J. Damaren, Karim Mekhail
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/4320e998628b46a9b1f9a18feb648d85
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spelling oai:doaj.org-article:4320e998628b46a9b1f9a18feb648d852021-12-02T15:33:43ZNuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair10.1038/s41467-018-05009-72041-1723https://doaj.org/article/4320e998628b46a9b1f9a18feb648d852018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05009-7https://doaj.org/toc/2041-1723Following DNA damage, different processes come to action to aid repair. The authors here find that microtubule filaments within the cell nucleus capture and non-randomly mobilize damaged chromatin to mediate DNA repair.Roxanne OshidariJonathan StreckerDaniel K. C. ChungKaran J. AbrahamJanet N. Y. ChanChristopher J. DamarenKarim MekhailNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Roxanne Oshidari
Jonathan Strecker
Daniel K. C. Chung
Karan J. Abraham
Janet N. Y. Chan
Christopher J. Damaren
Karim Mekhail
Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
description Following DNA damage, different processes come to action to aid repair. The authors here find that microtubule filaments within the cell nucleus capture and non-randomly mobilize damaged chromatin to mediate DNA repair.
format article
author Roxanne Oshidari
Jonathan Strecker
Daniel K. C. Chung
Karan J. Abraham
Janet N. Y. Chan
Christopher J. Damaren
Karim Mekhail
author_facet Roxanne Oshidari
Jonathan Strecker
Daniel K. C. Chung
Karan J. Abraham
Janet N. Y. Chan
Christopher J. Damaren
Karim Mekhail
author_sort Roxanne Oshidari
title Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
title_short Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
title_full Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
title_fullStr Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
title_full_unstemmed Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
title_sort nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote dna repair
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/4320e998628b46a9b1f9a18feb648d85
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