Chemoprophylaxis vaccination with a Plasmodium liver stage autophagy mutant affords enhanced and long-lasting protection
Abstract Genetically attenuated sporozoite vaccines can elicit long-lasting protection against malaria but pose risks of breakthrough infection. Chemoprophylaxis vaccination (CVac) has proven to be the most effective vaccine strategy against malaria. Here, we demonstrate that a liver stage-specific...
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Autores principales: | Tejram Sahu, Ella J. Gehrke, Yevel Flores-Garcia, Godfree Mlambo, Julia D. Romano, Isabelle Coppens |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/432db3d909be41fbba6bddb8eb40f52c |
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