Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD

How do individual differences affect vulnerability to developing post-traumatic stress disorder (PTSD)? Here, using longitudinal testing in a rat model of PTSD, the authors show patterns of pre-trauma brain connectivity and behaviors that predict PTSD-like responses to trauma exposure.

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Autores principales: David Dopfel, Pablo D. Perez, Alexander Verbitsky, Hector Bravo-Rivera, Yuncong Ma, Gregory J. Quirk, Nanyin Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/4333c50c454e4bad9388d3e0dbe266ec
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Sumario:How do individual differences affect vulnerability to developing post-traumatic stress disorder (PTSD)? Here, using longitudinal testing in a rat model of PTSD, the authors show patterns of pre-trauma brain connectivity and behaviors that predict PTSD-like responses to trauma exposure.