Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD
How do individual differences affect vulnerability to developing post-traumatic stress disorder (PTSD)? Here, using longitudinal testing in a rat model of PTSD, the authors show patterns of pre-trauma brain connectivity and behaviors that predict PTSD-like responses to trauma exposure.
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Nature Portfolio
2019
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oai:doaj.org-article:4333c50c454e4bad9388d3e0dbe266ec2021-12-02T17:31:37ZIndividual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD10.1038/s41467-019-09926-z2041-1723https://doaj.org/article/4333c50c454e4bad9388d3e0dbe266ec2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09926-zhttps://doaj.org/toc/2041-1723How do individual differences affect vulnerability to developing post-traumatic stress disorder (PTSD)? Here, using longitudinal testing in a rat model of PTSD, the authors show patterns of pre-trauma brain connectivity and behaviors that predict PTSD-like responses to trauma exposure.David DopfelPablo D. PerezAlexander VerbitskyHector Bravo-RiveraYuncong MaGregory J. QuirkNanyin ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019) |
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Science Q David Dopfel Pablo D. Perez Alexander Verbitsky Hector Bravo-Rivera Yuncong Ma Gregory J. Quirk Nanyin Zhang Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD |
description |
How do individual differences affect vulnerability to developing post-traumatic stress disorder (PTSD)? Here, using longitudinal testing in a rat model of PTSD, the authors show patterns of pre-trauma brain connectivity and behaviors that predict PTSD-like responses to trauma exposure. |
format |
article |
author |
David Dopfel Pablo D. Perez Alexander Verbitsky Hector Bravo-Rivera Yuncong Ma Gregory J. Quirk Nanyin Zhang |
author_facet |
David Dopfel Pablo D. Perez Alexander Verbitsky Hector Bravo-Rivera Yuncong Ma Gregory J. Quirk Nanyin Zhang |
author_sort |
David Dopfel |
title |
Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD |
title_short |
Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD |
title_full |
Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD |
title_fullStr |
Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD |
title_full_unstemmed |
Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD |
title_sort |
individual variability in behavior and functional networks predicts vulnerability using an animal model of ptsd |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/4333c50c454e4bad9388d3e0dbe266ec |
work_keys_str_mv |
AT daviddopfel individualvariabilityinbehaviorandfunctionalnetworkspredictsvulnerabilityusingananimalmodelofptsd AT pablodperez individualvariabilityinbehaviorandfunctionalnetworkspredictsvulnerabilityusingananimalmodelofptsd AT alexanderverbitsky individualvariabilityinbehaviorandfunctionalnetworkspredictsvulnerabilityusingananimalmodelofptsd AT hectorbravorivera individualvariabilityinbehaviorandfunctionalnetworkspredictsvulnerabilityusingananimalmodelofptsd AT yuncongma individualvariabilityinbehaviorandfunctionalnetworkspredictsvulnerabilityusingananimalmodelofptsd AT gregoryjquirk individualvariabilityinbehaviorandfunctionalnetworkspredictsvulnerabilityusingananimalmodelofptsd AT nanyinzhang individualvariabilityinbehaviorandfunctionalnetworkspredictsvulnerabilityusingananimalmodelofptsd |
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1718380548050649088 |