miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer

Código QR

miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer

Abstract The epithelial-mesenchymal transition (EMT) contributes to various processes in cancer progression, such as metastasis and drug resistance. Since we have already established a cell-based reporter system for identifying EMT-suppressive microRNAs (miRNAs) in the pancreatic cancer cell line Pa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hidekazu Hiramoto, Tomoki Muramatsu, Daisuke Ichikawa, Kousuke Tanimoto, Satoru Yasukawa, Eigo Otsuji, Johji Inazawa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4339122529b842ef8da00f3593f1db2e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients
por: Dorota Jesionek-Kupnicka, et al.
Publicado: (2019)

Age-Related Exosomal and Endogenous Expression Patterns of miR-1, miR-133a, miR-133b, and miR-206 in Skeletal Muscles
por: Chrystalla Mytidou, et al.
Publicado: (2021)

A mouse model of miR-96, miR-182 and miR-183 misexpression implicates miRNAs in cochlear cell fate and homeostasis
por: Michael D. Weston, et al.
Publicado: (2018)

miR-125a, miR-139 and miR-324 contribute to Urocortin protection against myocardial ischemia-reperfusion injury
por: Ignacio Díaz, et al.
Publicado: (2017)

Significance of miR-141 and miR-340 in cervical squamous cell carcinoma
por: Li Wenting, et al.
Publicado: (2021)

Decreased expression of miR-21, miR-26a, miR-29a, and miR-142-3p in CD4⁺ T cells and peripheral blood from tuberculosis patients.
por: Katja Kleinsteuber, et al.
Publicado: (2013)

Association Analysis Between the Functional Single Nucleotide Variants in miR-146a, miR-196a-2, miR-499a, and miR-612 With Acute Lymphoblastic Leukemia
por: Silvia Jiménez-Morales, et al.
Publicado: (2021)

Circulating miR-21, miR-29a, and miR-126 are associated with premature death risk due to cancer and cardiovascular disease: the JACC Study
por: Hiroya Yamada, et al.
Publicado: (2021)

Simultaneous downregulation of miR-21 and upregulation of miR-7 has anti-tumor efficacy
por: Deepak Bhere, et al.
Publicado: (2020)

Circulating miR-15a and miR-222 as Potential Biomarkers of Type 2 Diabetes
por: Sadeghzadeh S, et al.
Publicado: (2020)

Plasma Level Of miR-21 And miR-451 In Primary And Recurrent Breast Cancer Patients
por: Motamedi M, et al.
Publicado: (2019)

INVESTIGATION OF SALIVARY miR-9, miR-34a ve miR-196a LEVELS IN FANCONI ANEMIA AND ORAL SQUAMOUS CELL CARCINOMA PATIENTS
por: Zisan Asal Kilic, et al.
Publicado: (2021)

Neurodevelopment regulators miR-137 and miR-34 family as biomarkers for early and adult onset schizophrenia
por: Bao-Yu Chen, et al.
Publicado: (2021)

miR-12 and miR-124 contribute to defined early phases of long-lasting and transient memory
por: Julia Michely, et al.
Publicado: (2017)

miR-17 acts as a tumor suppressor by negatively regulating the miR-17-92 cluster
por: Yan Sweat, et al.
Publicado: (2021)

Haplotype distribution and evolutionary pattern of miR-17 and miR-124 families based on population analysis.
por: Li Guo, et al.
Publicado: (2009)

Children’s screen time alters the expression of saliva extracellular miR-222 and miR-146a
por: Annette Vriens, et al.
Publicado: (2018)

Dysregulation of NCAPG, KNL1, miR-148a-3p, miR-193b-3p, and miR-1179 may contribute to the progression of gastric cancer
por: Song,Bin, et al.
Publicado: (2018)

Triple negative aggressive phenotype controlled by miR-135b and miR-365: new theranostics candidates
por: Gloria Bertoli, et al.
Publicado: (2021)

The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice.
por: Neri Mercatelli, et al.
Publicado: (2008)

Circulating miR-92b and miR-375 for monitoring the chemoresistance and prognosis of small cell lung cancer
por: Ming Li, et al.
Publicado: (2020)

Elevated plasma miR-133b and miR-221-3p as biomarkers for early Parkinson’s disease
por: Qihua Chen, et al.
Publicado: (2021)

The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression
por: Jian Huang, et al.
Publicado: (2019)

Overexpression of miR-142-5p and miR-155 in gastric mucosa-associated lymphoid tissue (MALT) lymphoma resistant to Helicobacter pylori eradication.
por: Yoshimasa Saito, et al.
Publicado: (2012)

MiR-124 and miR-506 are involved in the decline of protein C in children with extra-hepatic portal vein obstruction
por: Jin-Shan Zhang, et al.
Publicado: (2021)

Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b
por: Sunglim Cho, et al.
Publicado: (2018)

miR-143 and miR-145 disrupt the cervical epithelial barrier through dysregulation of cell adhesion, apoptosis and proliferation
por: Lauren Anton, et al.
Publicado: (2017)

Ultraconserved element uc.372 drives hepatic lipid accumulation by suppressing miR-195/miR4668 maturation
por: Jun Guo, et al.
Publicado: (2018)

Genome-wide analysis of the SPL/miR156 module and its interaction with the AP2/miR172 unit in barley
por: Rajiv K. Tripathi, et al.
Publicado: (2018)

Circulating miR-30a-5p and miR-182-5p in Prediabetes and Screen-Detected Diabetes Mellitus
por: Weale CJ, et al.
Publicado: (2020)

Chronic administration of proanthocyanidins or docosahexaenoic acid reverses the increase of miR-33a and miR-122 in dyslipidemic obese rats.
por: Laura Baselga-Escudero, et al.
Publicado: (2013)

Circ_0092367 Inhibits EMT and Gemcitabine Resistance in Pancreatic Cancer via Regulating the miR-1206/ESRP1 Axis
por: Shuo Yu, et al.
Publicado: (2021)

miR-148 regulates Mitf in melanoma cells.
por: Benedikta S Haflidadóttir, et al.
Publicado: (2010)

Roles of miR-210 in the pathogenesis of pre-eclampsia
por: Jiyun Li, et al.
Publicado: (2018)

MiR-125 Family in Cardiovascular and Cerebrovascular Diseases
por: Yang Wang, et al.
Publicado: (2021)

Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer
por: Taisuke Imamura, et al.
Publicado: (2017)

Overexpression of miR125b Promotes Osteoporosis Through miR-125b-TRAF6 Pathway in Postmenopausal Ovariectomized Rats
por: Wang G, et al.
Publicado: (2021)

Bevacizumab confers significant improvements in survival for ovarian cancer patients with low miR-25 expression and high miR-142 expression
por: Jun Li, et al.
Publicado: (2021)

Synergistic post-transcriptional regulation of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) by miR-101 and miR-494 specific binding.
por: Francesca Megiorni, et al.
Publicado: (2011)

miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models
por: Estefania Cerro-Herreros, et al.
Publicado: (2018)