Origin of the omnipotence of eukaryotic release factor 1

The eukaryotic release factor eRF1 is able to recognize the three stop codons UAA, UAG and UGA with high accuracy, while discriminating against near-cognate codons. Here the authors use molecular dynamic simulation to provide insight into the molecular basis behind the remarkable codon specificity o...

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Autores principales:	Christoffer Lind, Ana Oliveira, Johan Åqvist
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/433a1ca0112148518b78c6acfcf20c96
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spelling	oai:doaj.org-article:433a1ca0112148518b78c6acfcf20c962021-12-02T17:06:12ZOrigin of the omnipotence of eukaryotic release factor 110.1038/s41467-017-01757-02041-1723https://doaj.org/article/433a1ca0112148518b78c6acfcf20c962017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01757-0https://doaj.org/toc/2041-1723The eukaryotic release factor eRF1 is able to recognize the three stop codons UAA, UAG and UGA with high accuracy, while discriminating against near-cognate codons. Here the authors use molecular dynamic simulation to provide insight into the molecular basis behind the remarkable codon specificity of eRF1.Christoffer LindAna OliveiraJohan ÅqvistNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christoffer Lind Ana Oliveira Johan Åqvist Origin of the omnipotence of eukaryotic release factor 1
description	The eukaryotic release factor eRF1 is able to recognize the three stop codons UAA, UAG and UGA with high accuracy, while discriminating against near-cognate codons. Here the authors use molecular dynamic simulation to provide insight into the molecular basis behind the remarkable codon specificity of eRF1.
format	article
author	Christoffer Lind Ana Oliveira Johan Åqvist
author_facet	Christoffer Lind Ana Oliveira Johan Åqvist
author_sort	Christoffer Lind
title	Origin of the omnipotence of eukaryotic release factor 1
title_short	Origin of the omnipotence of eukaryotic release factor 1
title_full	Origin of the omnipotence of eukaryotic release factor 1
title_fullStr	Origin of the omnipotence of eukaryotic release factor 1
title_full_unstemmed	Origin of the omnipotence of eukaryotic release factor 1
title_sort	origin of the omnipotence of eukaryotic release factor 1
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/433a1ca0112148518b78c6acfcf20c96
work_keys_str_mv	AT christofferlind originoftheomnipotenceofeukaryoticreleasefactor1 AT anaoliveira originoftheomnipotenceofeukaryoticreleasefactor1 AT johanaqvist originoftheomnipotenceofeukaryoticreleasefactor1
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Origin of the omnipotence of eukaryotic release factor 1

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