A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression

Chondrosarcomas are frequently aggressive, understanding the transcriptional changes associated with progression may help in developing new treatments. Here, the authors show that HIF-2α is increased in expression on progression and pharmacological inhibition of the protein together with chemotherap...

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Autores principales: Hyeonkyeong Kim, Yongsik Cho, Hyeon-Seop Kim, Donghyun Kang, Donghyeon Cheon, Yi-Jun Kim, Moon Jong Chang, Kyoung Min Lee, Chong Bum Chang, Seung-Baik Kang, Hyun Guy Kang, Jin-Hong Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/433db9da38794f3ca4269f360c059b88
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