Obstructive sleep apnea and psychomotor vigilance task performance

Salma Batool-Anwar,1 Stefanos N Kales,3,4 Sanjay R Patel,1 Vasileia Varvarigou,3 Pamela N DeYoung,2 Atul Malhotra21Department of Medicine, Sleep Disorders Program, Brigham and Women's Hospital, Boston, MA, USA; 2Pulmonary Critical Care Division, University of California San Diego, La Jolla,...

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Autores principales:	Batool-Anwar S, Kales SN, Patel SR, Varvarigou V, DeYoung PN, Malhotra A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495
Acceso en línea:	https://doaj.org/article/433e47d21eb44dfca5557ca63058e992
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spelling	oai:doaj.org-article:433e47d21eb44dfca5557ca63058e9922021-12-02T00:14:10ZObstructive sleep apnea and psychomotor vigilance task performance1179-1608https://doaj.org/article/433e47d21eb44dfca5557ca63058e9922014-05-01T00:00:00Zhttp://www.dovepress.com/obstructive-sleep-apnea-and-psychomotor-vigilance-task-performance-a16964https://doaj.org/toc/1179-1608 Salma Batool-Anwar,1 Stefanos N Kales,3,4 Sanjay R Patel,1 Vasileia Varvarigou,3 Pamela N DeYoung,2 Atul Malhotra21Department of Medicine, Sleep Disorders Program, Brigham and Women's Hospital, Boston, MA, USA; 2Pulmonary Critical Care Division, University of California San Diego, La Jolla, CA, USA; 3Department of Environmental and Occupational Medicine and Epidemiology, Harvard School of Public Health, Boston, 4Department of Occupational Medicine, The Cambridge Health Alliance, Cambridge, MA, USABackground: Obstructive sleep apnea (OSA) is a highly prevalent disorder with considerable morbidity and mortality. Vigilance and attentiveness are often impaired in OSA patients. In occupational medicine settings, subjective reports of sleepiness are notoriously inaccurate, making the identification of objective measures of vigilance potentially important for risk assessments of fitness for duty. In order to evaluate the effects of OSA on attentiveness and vigilance, we conducted a cross-sectional study to examine the association between OSA and psychomotor vigilance task (PVT) performance.Methods: Patients attending sleep clinics for evaluation of possible sleep apnea were recruited. The subjects underwent either a standard overnight laboratory polysomnography or home sleep study. Subjective daytime sleepiness was assessed by Epworth sleepiness scale, and vigilance was tested using a portable device. The participants were asked to respond to the PVT signals using their dominant hand. Each PVT administration lasted 10 minutes, with stimuli signals appearing randomly at variable intervals of 2–10 seconds.Results: Mean age of the participants was 46±15 years, and mean body mass index was 34.3±9.8 kg/m2. Participants with higher Epworth scores had worse PVT performance (P<0.05). In multivariate analyses, age, body mass index, and poor sleep efficiency (measured by Pittsburgh sleep quality index score) were associated with worse PVT performance (P<0.05). In contrast, PVT performance did not differ significantly across categories of apnea hypopnea index severity. Subgroup analysis demonstrated that women had worse performance on all PVT measures (P<0.05).Conclusion: PVT performance can be utilized for risk assessments of sleepiness and may be particularly useful among populations where subjective reports are unreliable.Keywords: obstructive sleep apnea, psychomotor vigilance test, sleepinessBatool-Anwar SKales SNPatel SRVarvarigou VDeYoung PNMalhotra ADove Medical PressarticlePsychiatryRC435-571Neurophysiology and neuropsychologyQP351-495ENNature and Science of Sleep, Vol 2014, Iss default, Pp 65-71 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495
spellingShingle	Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495 Batool-Anwar S Kales SN Patel SR Varvarigou V DeYoung PN Malhotra A Obstructive sleep apnea and psychomotor vigilance task performance
description	Salma Batool-Anwar,1 Stefanos N Kales,3,4 Sanjay R Patel,1 Vasileia Varvarigou,3 Pamela N DeYoung,2 Atul Malhotra21Department of Medicine, Sleep Disorders Program, Brigham and Women's Hospital, Boston, MA, USA; 2Pulmonary Critical Care Division, University of California San Diego, La Jolla, CA, USA; 3Department of Environmental and Occupational Medicine and Epidemiology, Harvard School of Public Health, Boston, 4Department of Occupational Medicine, The Cambridge Health Alliance, Cambridge, MA, USABackground: Obstructive sleep apnea (OSA) is a highly prevalent disorder with considerable morbidity and mortality. Vigilance and attentiveness are often impaired in OSA patients. In occupational medicine settings, subjective reports of sleepiness are notoriously inaccurate, making the identification of objective measures of vigilance potentially important for risk assessments of fitness for duty. In order to evaluate the effects of OSA on attentiveness and vigilance, we conducted a cross-sectional study to examine the association between OSA and psychomotor vigilance task (PVT) performance.Methods: Patients attending sleep clinics for evaluation of possible sleep apnea were recruited. The subjects underwent either a standard overnight laboratory polysomnography or home sleep study. Subjective daytime sleepiness was assessed by Epworth sleepiness scale, and vigilance was tested using a portable device. The participants were asked to respond to the PVT signals using their dominant hand. Each PVT administration lasted 10 minutes, with stimuli signals appearing randomly at variable intervals of 2–10 seconds.Results: Mean age of the participants was 46±15 years, and mean body mass index was 34.3±9.8 kg/m2. Participants with higher Epworth scores had worse PVT performance (P<0.05). In multivariate analyses, age, body mass index, and poor sleep efficiency (measured by Pittsburgh sleep quality index score) were associated with worse PVT performance (P<0.05). In contrast, PVT performance did not differ significantly across categories of apnea hypopnea index severity. Subgroup analysis demonstrated that women had worse performance on all PVT measures (P<0.05).Conclusion: PVT performance can be utilized for risk assessments of sleepiness and may be particularly useful among populations where subjective reports are unreliable.Keywords: obstructive sleep apnea, psychomotor vigilance test, sleepiness
format	article
author	Batool-Anwar S Kales SN Patel SR Varvarigou V DeYoung PN Malhotra A
author_facet	Batool-Anwar S Kales SN Patel SR Varvarigou V DeYoung PN Malhotra A
author_sort	Batool-Anwar S
title	Obstructive sleep apnea and psychomotor vigilance task performance
title_short	Obstructive sleep apnea and psychomotor vigilance task performance
title_full	Obstructive sleep apnea and psychomotor vigilance task performance
title_fullStr	Obstructive sleep apnea and psychomotor vigilance task performance
title_full_unstemmed	Obstructive sleep apnea and psychomotor vigilance task performance
title_sort	obstructive sleep apnea and psychomotor vigilance task performance
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/433e47d21eb44dfca5557ca63058e992
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Obstructive sleep apnea and psychomotor vigilance task performance

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