Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe

How glial cells, such as astrocytes, acquire their characteristic morphology during development is poorly understood. Here the authors describe the morphogenesis of astrocyte-like glia in the Drosophila optic lobe, and through a RNAi screen, they identify a transmembrane LRR protein–Lapsyn–that play...

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Autores principales: Benjamin Richier, Cristina de Miguel Vijandi, Stefanie Mackensen, Iris Salecker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4342d532fa0b49a2b9b04c6d9fd0ba93
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Sumario:How glial cells, such as astrocytes, acquire their characteristic morphology during development is poorly understood. Here the authors describe the morphogenesis of astrocyte-like glia in the Drosophila optic lobe, and through a RNAi screen, they identify a transmembrane LRR protein–Lapsyn–that plays a critical role in this process.