Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe

How glial cells, such as astrocytes, acquire their characteristic morphology during development is poorly understood. Here the authors describe the morphogenesis of astrocyte-like glia in the Drosophila optic lobe, and through a RNAi screen, they identify a transmembrane LRR protein–Lapsyn–that play...

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Autores principales:	Benjamin Richier, Cristina de Miguel Vijandi, Stefanie Mackensen, Iris Salecker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4342d532fa0b49a2b9b04c6d9fd0ba93
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spelling	oai:doaj.org-article:4342d532fa0b49a2b9b04c6d9fd0ba932021-12-02T13:27:22ZLapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe10.1038/s41467-017-00384-z2041-1723https://doaj.org/article/4342d532fa0b49a2b9b04c6d9fd0ba932017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00384-zhttps://doaj.org/toc/2041-1723How glial cells, such as astrocytes, acquire their characteristic morphology during development is poorly understood. Here the authors describe the morphogenesis of astrocyte-like glia in the Drosophila optic lobe, and through a RNAi screen, they identify a transmembrane LRR protein–Lapsyn–that plays a critical role in this process.Benjamin RichierCristina de Miguel VijandiStefanie MackensenIris SaleckerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benjamin Richier Cristina de Miguel Vijandi Stefanie Mackensen Iris Salecker Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe
description	How glial cells, such as astrocytes, acquire their characteristic morphology during development is poorly understood. Here the authors describe the morphogenesis of astrocyte-like glia in the Drosophila optic lobe, and through a RNAi screen, they identify a transmembrane LRR protein–Lapsyn–that plays a critical role in this process.
format	article
author	Benjamin Richier Cristina de Miguel Vijandi Stefanie Mackensen Iris Salecker
author_facet	Benjamin Richier Cristina de Miguel Vijandi Stefanie Mackensen Iris Salecker
author_sort	Benjamin Richier
title	Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe
title_short	Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe
title_full	Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe
title_fullStr	Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe
title_full_unstemmed	Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe
title_sort	lapsyn controls branch extension and positioning of astrocyte-like glia in the drosophila optic lobe
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4342d532fa0b49a2b9b04c6d9fd0ba93
work_keys_str_mv	AT benjaminrichier lapsyncontrolsbranchextensionandpositioningofastrocytelikegliainthedrosophilaopticlobe AT cristinademiguelvijandi lapsyncontrolsbranchextensionandpositioningofastrocytelikegliainthedrosophilaopticlobe AT stefaniemackensen lapsyncontrolsbranchextensionandpositioningofastrocytelikegliainthedrosophilaopticlobe AT irissalecker lapsyncontrolsbranchextensionandpositioningofastrocytelikegliainthedrosophilaopticlobe
_version_	1718392971084169216

Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe

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