Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes

Memory B cells need to be reactivated to produce high affinity antibody responses on subsequent antigen encounters. Here the authors show that memory B cells localise to lymph node subcapsular proliferative foci (SPF), which have distinct properties from the germinal centre, for rapid expansion and...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Imogen Moran, Akira Nguyen, Weng Hua Khoo, Danyal Butt, Katherine Bourne, Clara Young, Jana R. Hermes, Maté Biro, Gary Gracie, Cindy S. Ma, C. Mee Ling Munier, Fabio Luciani, John Zaunders, Andrew Parker, Anthony D. Kelleher, Stuart G. Tangye, Peter I. Croucher, Robert Brink, Mark N. Read, Tri Giang Phan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/434c7143b0dc490799e9dd7d746d107f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:434c7143b0dc490799e9dd7d746d107f
record_format	dspace
spelling	oai:doaj.org-article:434c7143b0dc490799e9dd7d746d107f2021-12-02T15:34:50ZMemory B cells are reactivated in subcapsular proliferative foci of lymph nodes10.1038/s41467-018-05772-72041-1723https://doaj.org/article/434c7143b0dc490799e9dd7d746d107f2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05772-7https://doaj.org/toc/2041-1723Memory B cells need to be reactivated to produce high affinity antibody responses on subsequent antigen encounters. Here the authors show that memory B cells localise to lymph node subcapsular proliferative foci (SPF), which have distinct properties from the germinal centre, for rapid expansion and the induction of B memory responses.Imogen MoranAkira NguyenWeng Hua KhooDanyal ButtKatherine BourneClara YoungJana R. HermesMaté BiroGary GracieCindy S. MaC. Mee Ling MunierFabio LucianiJohn ZaundersAndrew ParkerAnthony D. KelleherStuart G. TangyePeter I. CroucherRobert BrinkMark N. ReadTri Giang PhanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Imogen Moran Akira Nguyen Weng Hua Khoo Danyal Butt Katherine Bourne Clara Young Jana R. Hermes Maté Biro Gary Gracie Cindy S. Ma C. Mee Ling Munier Fabio Luciani John Zaunders Andrew Parker Anthony D. Kelleher Stuart G. Tangye Peter I. Croucher Robert Brink Mark N. Read Tri Giang Phan Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes
description	Memory B cells need to be reactivated to produce high affinity antibody responses on subsequent antigen encounters. Here the authors show that memory B cells localise to lymph node subcapsular proliferative foci (SPF), which have distinct properties from the germinal centre, for rapid expansion and the induction of B memory responses.
format	article
author	Imogen Moran Akira Nguyen Weng Hua Khoo Danyal Butt Katherine Bourne Clara Young Jana R. Hermes Maté Biro Gary Gracie Cindy S. Ma C. Mee Ling Munier Fabio Luciani John Zaunders Andrew Parker Anthony D. Kelleher Stuart G. Tangye Peter I. Croucher Robert Brink Mark N. Read Tri Giang Phan
author_facet	Imogen Moran Akira Nguyen Weng Hua Khoo Danyal Butt Katherine Bourne Clara Young Jana R. Hermes Maté Biro Gary Gracie Cindy S. Ma C. Mee Ling Munier Fabio Luciani John Zaunders Andrew Parker Anthony D. Kelleher Stuart G. Tangye Peter I. Croucher Robert Brink Mark N. Read Tri Giang Phan
author_sort	Imogen Moran
title	Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes
title_short	Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes
title_full	Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes
title_fullStr	Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes
title_full_unstemmed	Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes
title_sort	memory b cells are reactivated in subcapsular proliferative foci of lymph nodes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/434c7143b0dc490799e9dd7d746d107f
work_keys_str_mv	AT imogenmoran memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT akiranguyen memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT wenghuakhoo memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT danyalbutt memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT katherinebourne memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT clarayoung memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT janarhermes memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT matebiro memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT garygracie memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT cindysma memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT cmeelingmunier memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT fabioluciani memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT johnzaunders memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT andrewparker memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT anthonydkelleher memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT stuartgtangye memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT petericroucher memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT robertbrink memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT marknread memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes AT trigiangphan memorybcellsarereactivatedinsubcapsularproliferativefocioflymphnodes
_version_	1718386714757562368

Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes

Ejemplares similares