IRE1-Mediated Unfolded Protein Response Promotes the Replication of Tick-Borne Flaviviruses in a Virus and Cell-Type Dependent Manner

Tick-borne flaviviruses (TBFV) can cause severe neurological complications in humans, but differences in tissue tropism and pathogenicity have been described for individual virus strains. Viral protein synthesis leads to the induction of the unfolded protein response (UPR) within infected cells. The...

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Bibliographic Details
Main Authors: Veronika J. M. Breitkopf, Gerhard Dobler, Peter Claus, Hassan Y. Naim, Imke Steffen
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/435a7a686d3b456e9f0a1edd3300a685
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