Cortical astrocytes develop in a plastic manner at both clonal and cellular levels
Previous studies on astrocyte development have led to controversial results due to a lack of pertinent tools. Here, authors analyze large numbers of astrocyte clones generated by nearby cortical progenitors using the MAGIC Markers strategy and ChroMS 3D imaging, and show that clonally-related astroc...
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Nature Portfolio
2019
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oai:doaj.org-article:435d94e6bca044b89496f3445b4f4c832021-12-02T17:02:11ZCortical astrocytes develop in a plastic manner at both clonal and cellular levels10.1038/s41467-019-12791-52041-1723https://doaj.org/article/435d94e6bca044b89496f3445b4f4c832019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12791-5https://doaj.org/toc/2041-1723Previous studies on astrocyte development have led to controversial results due to a lack of pertinent tools. Here, authors analyze large numbers of astrocyte clones generated by nearby cortical progenitors using the MAGIC Markers strategy and ChroMS 3D imaging, and show that clonally-related astrocytes organize in a non-stereotyped manner and that cortical astrocyte subtypes are not intrinsically specified.Solène ClavreulLamiae AbdeladimEdwin Hernández-GarzónDragos NiculescuJason DurandSio-Hoï IengRaphaëlle BarryGilles BonventoEmmanuel BeaurepaireJean LivetKarine LoulierNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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Science Q Solène Clavreul Lamiae Abdeladim Edwin Hernández-Garzón Dragos Niculescu Jason Durand Sio-Hoï Ieng Raphaëlle Barry Gilles Bonvento Emmanuel Beaurepaire Jean Livet Karine Loulier Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
description |
Previous studies on astrocyte development have led to controversial results due to a lack of pertinent tools. Here, authors analyze large numbers of astrocyte clones generated by nearby cortical progenitors using the MAGIC Markers strategy and ChroMS 3D imaging, and show that clonally-related astrocytes organize in a non-stereotyped manner and that cortical astrocyte subtypes are not intrinsically specified. |
format |
article |
author |
Solène Clavreul Lamiae Abdeladim Edwin Hernández-Garzón Dragos Niculescu Jason Durand Sio-Hoï Ieng Raphaëlle Barry Gilles Bonvento Emmanuel Beaurepaire Jean Livet Karine Loulier |
author_facet |
Solène Clavreul Lamiae Abdeladim Edwin Hernández-Garzón Dragos Niculescu Jason Durand Sio-Hoï Ieng Raphaëlle Barry Gilles Bonvento Emmanuel Beaurepaire Jean Livet Karine Loulier |
author_sort |
Solène Clavreul |
title |
Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
title_short |
Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
title_full |
Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
title_fullStr |
Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
title_full_unstemmed |
Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
title_sort |
cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/435d94e6bca044b89496f3445b4f4c83 |
work_keys_str_mv |
AT soleneclavreul corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT lamiaeabdeladim corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT edwinhernandezgarzon corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT dragosniculescu corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT jasondurand corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT siohoiieng corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT raphaellebarry corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT gillesbonvento corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT emmanuelbeaurepaire corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT jeanlivet corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels AT karineloulier corticalastrocytesdevelopinaplasticmanneratbothclonalandcellularlevels |
_version_ |
1718381963387076608 |