Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix

Yuichi Matsushima et al. revealed that Human ATP-dependent Lon protease (LONP1), a mitochondrial protease with unfolding activity, serves as a gatekeeper for several mitochondrial matrix entering proteins: supporting the folding of required proteins and degrading the aberrant ones.

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Autores principales:	Yuichi Matsushima, Kazuya Takahashi, Song Yue, Yuki Fujiyoshi, Hideaki Yoshioka, Masamune Aihara, Daiki Setoyama, Takeshi Uchiumi, Satoshi Fukuchi, Dongchon Kang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/4361637922cb446fabdfce70c5a5a15d
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spelling	oai:doaj.org-article:4361637922cb446fabdfce70c5a5a15d2021-12-02T15:10:45ZMitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix10.1038/s42003-021-02498-z2399-3642https://doaj.org/article/4361637922cb446fabdfce70c5a5a15d2021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02498-zhttps://doaj.org/toc/2399-3642Yuichi Matsushima et al. revealed that Human ATP-dependent Lon protease (LONP1), a mitochondrial protease with unfolding activity, serves as a gatekeeper for several mitochondrial matrix entering proteins: supporting the folding of required proteins and degrading the aberrant ones.Yuichi MatsushimaKazuya TakahashiSong YueYuki FujiyoshiHideaki YoshiokaMasamune AiharaDaiki SetoyamaTakeshi UchiumiSatoshi FukuchiDongchon KangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Yuichi Matsushima Kazuya Takahashi Song Yue Yuki Fujiyoshi Hideaki Yoshioka Masamune Aihara Daiki Setoyama Takeshi Uchiumi Satoshi Fukuchi Dongchon Kang Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix
description	Yuichi Matsushima et al. revealed that Human ATP-dependent Lon protease (LONP1), a mitochondrial protease with unfolding activity, serves as a gatekeeper for several mitochondrial matrix entering proteins: supporting the folding of required proteins and degrading the aberrant ones.
format	article
author	Yuichi Matsushima Kazuya Takahashi Song Yue Yuki Fujiyoshi Hideaki Yoshioka Masamune Aihara Daiki Setoyama Takeshi Uchiumi Satoshi Fukuchi Dongchon Kang
author_facet	Yuichi Matsushima Kazuya Takahashi Song Yue Yuki Fujiyoshi Hideaki Yoshioka Masamune Aihara Daiki Setoyama Takeshi Uchiumi Satoshi Fukuchi Dongchon Kang
author_sort	Yuichi Matsushima
title	Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix
title_short	Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix
title_full	Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix
title_fullStr	Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix
title_full_unstemmed	Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix
title_sort	mitochondrial lon protease is a gatekeeper for proteins newly imported into the matrix
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4361637922cb446fabdfce70c5a5a15d
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Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix

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