Body weight regulation of a low molecular weight xanthan gum on normal mice via gut microbiota

Properties of thickening, emulsification and suspension make xanthan gum is widely used in foods and other industries, but effects of xanthan oligosaccharide or low molecular weight xanthan gum (LW-XG) on the nutrition of human body are rarely investigated. Presently, body weight regulation effect o...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Xincheng Sun, Chengxin Zhao, Xuyang Hu, Jingnan Zhang, Suyue Xu, XiaYing Li, Yanhong Bai, Xiaogen Zhang, Jinqiang Hu, Qi Sun, Zichao Wang
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://doaj.org/article/436512cd07c147c7a6fa391785d23cc9
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Properties of thickening, emulsification and suspension make xanthan gum is widely used in foods and other industries, but effects of xanthan oligosaccharide or low molecular weight xanthan gum (LW-XG) on the nutrition of human body are rarely investigated. Presently, body weight regulation effect of a LW-XG on male mice was assayed. Results showed that LW-XG was safe to Caco-2 cells and mice, and increased mice body weight gain from 10.78 ± 2.15 g to 13.28 ± 1.97 g. Meanwhile, the acetate, propionate, butyrate and total short-chain fatty acids (SCFAs) contents increased from 25.13 ± 1.28 μmol/g, 11.28 ± 0.81 μmol/g, 7.85 ± 0.43 μmol/g and 44.26 ± 1.85 μmol/g to 41.76 ± 1.08 μmol/g, 19.84 ± 0.97 μmol/g, 12.58 ± 0.26 μmol/g and 74.18 ± 1.72 μmol/g, respectively. Furthermore, LW-XG increased the abundance and diversity of gut microbiota, and Firmicutes/Bacteroidetes ratio was significantly increased from 0.3547 to 1.5371.