Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly.
Novel therapies are urgently needed against hepatitis C virus infection (HCV), a major global health problem. The current model of infectious virus production suggests that HCV virions are assembled on or near the surface of lipid droplets, acquire their envelope at the ER, and egress through the se...
Enregistré dans:
Auteurs principaux: | Gregory Neveu, Rina Barouch-Bentov, Amotz Ziv-Av, Doron Gerber, Yves Jacob, Shirit Einav |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/4376c78e7b4d4267a0a211fee5e30e1d |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Hepatitis C Virus Proteins Interact with the Endosomal Sorting Complex Required for Transport (ESCRT) Machinery via Ubiquitination To Facilitate Viral Envelopment
par: Rina Barouch-Bentov, et autres
Publié: (2016) -
Erratum for Barouch-Bentov et al., “Hepatitis C Virus Proteins Interact with the Endosomal Sorting Complex Required for Transport (ESCRT) Machinery via Ubiquitination To Facilitate Viral Envelopment”
par: Rina Barouch-Bentov, et autres
Publié: (2018) -
Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release
par: Fei Xiao, et autres
Publié: (2018) -
Role of PDZ-binding motif from West Nile virus NS5 protein on viral replication
par: Emilie Giraud, et autres
Publié: (2021) -
Helix 8 is the essential structural motif of mechanosensitive GPCRs
par: Serap Erdogmus, et autres
Publié: (2019)