Rational treatment of patients with functional dyspepsia

Functional dyspepsia is one of the most common functional disorders of the gastrointestinal tract, which resulted from impaired motor skills, visceral hypersensitivity, increased mucosal permeability, disorders of the autonomic nervous system, etc. There is no specific therapy for this disease, whic...

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Autores principales:	Alexander S. Kazakov, Sergey K. Zyryanov, Elena A. Ushkalova, Elena K. Nasretdinova
Formato:	article
Lenguaje:	RU
Publicado:	"Consilium Medicum" Publishing house 2021
Materias:	functional dyspepsia prokinetics meta-analysis rational pharmacotherapy Medicine R
Acceso en línea:	https://doaj.org/article/437a25e06f4f47719522d5a1f8ff48ba
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spelling	oai:doaj.org-article:437a25e06f4f47719522d5a1f8ff48ba2021-12-01T12:22:36ZRational treatment of patients with functional dyspepsia0040-36602309-534210.26442/00403660.2021.08.200984https://doaj.org/article/437a25e06f4f47719522d5a1f8ff48ba2021-08-01T00:00:00Zhttps://ter-arkhiv.ru/0040-3660/article/viewFile/79597/60213https://doaj.org/toc/0040-3660https://doaj.org/toc/2309-5342Functional dyspepsia is one of the most common functional disorders of the gastrointestinal tract, which resulted from impaired motor skills, visceral hypersensitivity, increased mucosal permeability, disorders of the autonomic nervous system, etc. There is no specific therapy for this disease, which often leads to the irrational use of various groups of drugs. Drug therapy is recommended only during periods of symptoms. The main options of pharmacotherapy include the use of proton pump inhibitors, phytotherapeutic drugs, eradication therapy of Helicobacter pylori. Against the background of possible motor disorders, prokinetics are also one of the possible treatment options, but cisapride has long been withdrawn from sale due to cardiotoxicity, the use of domperidone and metoclopramide is limited due to side effects, especially with long-term therapy, so currently the only prokinetic that can be used in everyday clinical practice is itopride. In refractory cases, tricyclic antidepressants and psychotherapeutic approaches are another effective treatment option.Alexander S. KazakovSergey K. ZyryanovElena A. UshkalovaElena K. Nasretdinova"Consilium Medicum" Publishing housearticlefunctional dyspepsiaprokineticsmeta-analysisrational pharmacotherapyMedicineRRUТерапевтический архив, Vol 93, Iss 8, Pp 982-985 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	functional dyspepsia prokinetics meta-analysis rational pharmacotherapy Medicine R
spellingShingle	functional dyspepsia prokinetics meta-analysis rational pharmacotherapy Medicine R Alexander S. Kazakov Sergey K. Zyryanov Elena A. Ushkalova Elena K. Nasretdinova Rational treatment of patients with functional dyspepsia
description	Functional dyspepsia is one of the most common functional disorders of the gastrointestinal tract, which resulted from impaired motor skills, visceral hypersensitivity, increased mucosal permeability, disorders of the autonomic nervous system, etc. There is no specific therapy for this disease, which often leads to the irrational use of various groups of drugs. Drug therapy is recommended only during periods of symptoms. The main options of pharmacotherapy include the use of proton pump inhibitors, phytotherapeutic drugs, eradication therapy of Helicobacter pylori. Against the background of possible motor disorders, prokinetics are also one of the possible treatment options, but cisapride has long been withdrawn from sale due to cardiotoxicity, the use of domperidone and metoclopramide is limited due to side effects, especially with long-term therapy, so currently the only prokinetic that can be used in everyday clinical practice is itopride. In refractory cases, tricyclic antidepressants and psychotherapeutic approaches are another effective treatment option.
format	article
author	Alexander S. Kazakov Sergey K. Zyryanov Elena A. Ushkalova Elena K. Nasretdinova
author_facet	Alexander S. Kazakov Sergey K. Zyryanov Elena A. Ushkalova Elena K. Nasretdinova
author_sort	Alexander S. Kazakov
title	Rational treatment of patients with functional dyspepsia
title_short	Rational treatment of patients with functional dyspepsia
title_full	Rational treatment of patients with functional dyspepsia
title_fullStr	Rational treatment of patients with functional dyspepsia
title_full_unstemmed	Rational treatment of patients with functional dyspepsia
title_sort	rational treatment of patients with functional dyspepsia
publisher	"Consilium Medicum" Publishing house
publishDate	2021
url	https://doaj.org/article/437a25e06f4f47719522d5a1f8ff48ba
work_keys_str_mv	AT alexanderskazakov rationaltreatmentofpatientswithfunctionaldyspepsia AT sergeykzyryanov rationaltreatmentofpatientswithfunctionaldyspepsia AT elenaaushkalova rationaltreatmentofpatientswithfunctionaldyspepsia AT elenaknasretdinova rationaltreatmentofpatientswithfunctionaldyspepsia
_version_	1718405169459232768

Rational treatment of patients with functional dyspepsia

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