The first case of Janibacter hoylei bacteremia in an adult

The Janibacter species are Gram positive, coryneform bacteria that belong to the Actinobacteria phylum and have been linked to bacteremia in immunocompromised children. We present the first documented adult case of Janibacter hoylei bacteremia. The patient was a 52-year-old woman with a history of r...

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Autores principales:	Varun Moktan, Sammer Elwasila, Goyal Umadat, D. Jane Hata, Diana Meza, Robin Patel, Claudia Libertin, Lisa Brumble
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Bacteremia Janibacter Malignancy Immunosuppression Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/437bc7c4831444048cd26b81310feba5
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spelling	oai:doaj.org-article:437bc7c4831444048cd26b81310feba52021-11-24T04:30:52ZThe first case of Janibacter hoylei bacteremia in an adult2214-250910.1016/j.idcr.2021.e01339https://doaj.org/article/437bc7c4831444048cd26b81310feba52021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S221425092100295Xhttps://doaj.org/toc/2214-2509The Janibacter species are Gram positive, coryneform bacteria that belong to the Actinobacteria phylum and have been linked to bacteremia in immunocompromised children. We present the first documented adult case of Janibacter hoylei bacteremia. The patient was a 52-year-old woman with a history of recurrent Clostridioides difficile infection, sinus tachycardia and high-risk AML who had been admitted one month prior to presentation for matched unrelated donor hematopoietic stem cell transplant with reduced intensity fludarabine-melphalan. Thirty days post-transplant, the infectious disease team was consulted because blood cultures grew Janibacter hoylei, from one of two blood cultures It took nine days to identify the species. She was treated with linezolid and imipenem. Janibacter are rarely implicated in human pathology, and therein, usually identified in the context of malignancy and relative immunosuppression. J. hoylei was only previously reported from the bloodstream of a previously healthy 8-week-old infant without underlying medical conditions. Antimicrobial susceptibility testing is challenging as only in vitro susceptibility testing of Janibacter terrae has been reported. Given these challenges, it is our hope to illustrate the clinical approach to diagnosis as well as subsequent recommendations for treatment in a particularly challenging case of bacteremia in an AML patient.Varun MoktanSammer ElwasilaGoyal UmadatD. Jane HataDiana MezaRobin PatelClaudia LibertinLisa BrumbleElsevierarticleBacteremiaJanibacterMalignancyImmunosuppressionInfectious and parasitic diseasesRC109-216ENIDCases, Vol 26, Iss , Pp e01339- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Bacteremia Janibacter Malignancy Immunosuppression Infectious and parasitic diseases RC109-216
spellingShingle	Bacteremia Janibacter Malignancy Immunosuppression Infectious and parasitic diseases RC109-216 Varun Moktan Sammer Elwasila Goyal Umadat D. Jane Hata Diana Meza Robin Patel Claudia Libertin Lisa Brumble The first case of Janibacter hoylei bacteremia in an adult
description	The Janibacter species are Gram positive, coryneform bacteria that belong to the Actinobacteria phylum and have been linked to bacteremia in immunocompromised children. We present the first documented adult case of Janibacter hoylei bacteremia. The patient was a 52-year-old woman with a history of recurrent Clostridioides difficile infection, sinus tachycardia and high-risk AML who had been admitted one month prior to presentation for matched unrelated donor hematopoietic stem cell transplant with reduced intensity fludarabine-melphalan. Thirty days post-transplant, the infectious disease team was consulted because blood cultures grew Janibacter hoylei, from one of two blood cultures It took nine days to identify the species. She was treated with linezolid and imipenem. Janibacter are rarely implicated in human pathology, and therein, usually identified in the context of malignancy and relative immunosuppression. J. hoylei was only previously reported from the bloodstream of a previously healthy 8-week-old infant without underlying medical conditions. Antimicrobial susceptibility testing is challenging as only in vitro susceptibility testing of Janibacter terrae has been reported. Given these challenges, it is our hope to illustrate the clinical approach to diagnosis as well as subsequent recommendations for treatment in a particularly challenging case of bacteremia in an AML patient.
format	article
author	Varun Moktan Sammer Elwasila Goyal Umadat D. Jane Hata Diana Meza Robin Patel Claudia Libertin Lisa Brumble
author_facet	Varun Moktan Sammer Elwasila Goyal Umadat D. Jane Hata Diana Meza Robin Patel Claudia Libertin Lisa Brumble
author_sort	Varun Moktan
title	The first case of Janibacter hoylei bacteremia in an adult
title_short	The first case of Janibacter hoylei bacteremia in an adult
title_full	The first case of Janibacter hoylei bacteremia in an adult
title_fullStr	The first case of Janibacter hoylei bacteremia in an adult
title_full_unstemmed	The first case of Janibacter hoylei bacteremia in an adult
title_sort	first case of janibacter hoylei bacteremia in an adult
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/437bc7c4831444048cd26b81310feba5
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The first case of Janibacter hoylei bacteremia in an adult

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