ASSESSMENT OF THE SPECIFIC LOCAL HUMORAL IMMUNITY IN PATIENTS WITH INFERTILITY INCLUDING CASES ASSOCIATED WITH GENITAL TUBERCULOSIS

Abstract. In order to optimize the detection and diagnosis of genital tuberculosis evaluation of the specific local antituberculosis immunity in 39 patients with infertility entered to the Department of Gynecology for the implementation of therapeutic and diagnostic laparoscopy has been carried out....

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Autores principales: A. V. Mordyk, T. I. Dolgyh, N. B. Frolova, A. A. Yakovleva
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Lenguaje:RU
Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2014
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Acceso en línea:https://doaj.org/article/439d1baa26784822923bee298c33a570
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spelling oai:doaj.org-article:439d1baa26784822923bee298c33a5702021-11-22T07:09:46ZASSESSMENT OF THE SPECIFIC LOCAL HUMORAL IMMUNITY IN PATIENTS WITH INFERTILITY INCLUDING CASES ASSOCIATED WITH GENITAL TUBERCULOSIS2220-76192313-739810.15789/2220-7619-2013-4-335-340https://doaj.org/article/439d1baa26784822923bee298c33a5702014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/142https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. In order to optimize the detection and diagnosis of genital tuberculosis evaluation of the specific local antituberculosis immunity in 39 patients with infertility entered to the Department of Gynecology for the implementation of therapeutic and diagnostic laparoscopy has been carried out. All patients were divided into 3 groups: the 1st one included patients with tubal-peritoneal infertility, the group 2 included patients with infertility not associated with the defeat of the fallopian tubes, the third group was presented by patients with tubal-peritoneal infertility associated with genital tuberculosis who completed the basic course of anti-tuberculosis treatment. It was established that in case of the tubal-peritoneal infertility the local humoral immunity was characterised by increasing of IgM in the whole peritoneal fluid. Among women who recovered from genital tuberculosis increasing of IgA and IgG to M. tuberculosis was revealed in contrast to patients with infertility not associated with damage of fallopian tubes (p < 0.05). In 25% of patients of the 1st group genital tuberculosis was diagnosed. The diagnostic criteria for early detection of genital tuberculosis were determined and the algorithm of genital tuberculosis identification have been proposed.A. V. MordykT. I. DolgyhN. B. FrolovaA. A. YakovlevaSankt-Peterburg : NIIÈM imeni Pasteraarticlespecific humoral immunityinfertilitygenital tuberculosisperitoneal fluidInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 3, Iss 4, Pp 335-340 (2014)
institution DOAJ
collection DOAJ
language RU
topic specific humoral immunity
infertility
genital tuberculosis
peritoneal fluid
Infectious and parasitic diseases
RC109-216
spellingShingle specific humoral immunity
infertility
genital tuberculosis
peritoneal fluid
Infectious and parasitic diseases
RC109-216
A. V. Mordyk
T. I. Dolgyh
N. B. Frolova
A. A. Yakovleva
ASSESSMENT OF THE SPECIFIC LOCAL HUMORAL IMMUNITY IN PATIENTS WITH INFERTILITY INCLUDING CASES ASSOCIATED WITH GENITAL TUBERCULOSIS
description Abstract. In order to optimize the detection and diagnosis of genital tuberculosis evaluation of the specific local antituberculosis immunity in 39 patients with infertility entered to the Department of Gynecology for the implementation of therapeutic and diagnostic laparoscopy has been carried out. All patients were divided into 3 groups: the 1st one included patients with tubal-peritoneal infertility, the group 2 included patients with infertility not associated with the defeat of the fallopian tubes, the third group was presented by patients with tubal-peritoneal infertility associated with genital tuberculosis who completed the basic course of anti-tuberculosis treatment. It was established that in case of the tubal-peritoneal infertility the local humoral immunity was characterised by increasing of IgM in the whole peritoneal fluid. Among women who recovered from genital tuberculosis increasing of IgA and IgG to M. tuberculosis was revealed in contrast to patients with infertility not associated with damage of fallopian tubes (p < 0.05). In 25% of patients of the 1st group genital tuberculosis was diagnosed. The diagnostic criteria for early detection of genital tuberculosis were determined and the algorithm of genital tuberculosis identification have been proposed.
format article
author A. V. Mordyk
T. I. Dolgyh
N. B. Frolova
A. A. Yakovleva
author_facet A. V. Mordyk
T. I. Dolgyh
N. B. Frolova
A. A. Yakovleva
author_sort A. V. Mordyk
title ASSESSMENT OF THE SPECIFIC LOCAL HUMORAL IMMUNITY IN PATIENTS WITH INFERTILITY INCLUDING CASES ASSOCIATED WITH GENITAL TUBERCULOSIS
title_short ASSESSMENT OF THE SPECIFIC LOCAL HUMORAL IMMUNITY IN PATIENTS WITH INFERTILITY INCLUDING CASES ASSOCIATED WITH GENITAL TUBERCULOSIS
title_full ASSESSMENT OF THE SPECIFIC LOCAL HUMORAL IMMUNITY IN PATIENTS WITH INFERTILITY INCLUDING CASES ASSOCIATED WITH GENITAL TUBERCULOSIS
title_fullStr ASSESSMENT OF THE SPECIFIC LOCAL HUMORAL IMMUNITY IN PATIENTS WITH INFERTILITY INCLUDING CASES ASSOCIATED WITH GENITAL TUBERCULOSIS
title_full_unstemmed ASSESSMENT OF THE SPECIFIC LOCAL HUMORAL IMMUNITY IN PATIENTS WITH INFERTILITY INCLUDING CASES ASSOCIATED WITH GENITAL TUBERCULOSIS
title_sort assessment of the specific local humoral immunity in patients with infertility including cases associated with genital tuberculosis
publisher Sankt-Peterburg : NIIÈM imeni Pastera
publishDate 2014
url https://doaj.org/article/439d1baa26784822923bee298c33a570
work_keys_str_mv AT avmordyk assessmentofthespecificlocalhumoralimmunityinpatientswithinfertilityincludingcasesassociatedwithgenitaltuberculosis
AT tidolgyh assessmentofthespecificlocalhumoralimmunityinpatientswithinfertilityincludingcasesassociatedwithgenitaltuberculosis
AT nbfrolova assessmentofthespecificlocalhumoralimmunityinpatientswithinfertilityincludingcasesassociatedwithgenitaltuberculosis
AT aayakovleva assessmentofthespecificlocalhumoralimmunityinpatientswithinfertilityincludingcasesassociatedwithgenitaltuberculosis
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