Mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures

Abstract The median palatal suture serves as a growth center for the maxilla; inadequate growth at this site causes malocclusion and dental crowding. However, the pattern formation mechanism of palatal sutures is poorly understood compared with that of calvarial sutures such as the sagittal suture....

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Autores principales:	Nobuhide Shibusawa, Yoshie Endo, Naoki Morimoto, Ichiro Takahashi, Takashi Miura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/43ab4ea2026f4c2e969859eae41abfce
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spelling	oai:doaj.org-article:43ab4ea2026f4c2e969859eae41abfce2021-12-02T17:39:19ZMathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures10.1038/s41598-021-88255-y2045-2322https://doaj.org/article/43ab4ea2026f4c2e969859eae41abfce2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88255-yhttps://doaj.org/toc/2045-2322Abstract The median palatal suture serves as a growth center for the maxilla; inadequate growth at this site causes malocclusion and dental crowding. However, the pattern formation mechanism of palatal sutures is poorly understood compared with that of calvarial sutures such as the sagittal suture. In the present study, therefore, we compared the morphological characteristics of sagittal and palatal sutures in human bone specimens. We found that palatal suture width was narrower than sagittal suture width, and the interdigitation amplitude of the palatal suture was lower than that of the sagittal suture. These tendencies were also observed in the neonatal stage. However, such differences were not observed in other animals such as chimpanzees and mice. We also used a mathematical model to reproduce the differences between palatal and sagittal sutures. After an extensive parameter search, we found two conditions that could generate the difference in interdigitation amplitude and suture width: bone differentiation threshold $$v_c$$ v c and growth speed c. We discuss possible biological interpretations of the observed pattern difference and its cause.Nobuhide ShibusawaYoshie EndoNaoki MorimotoIchiro TakahashiTakashi MiuraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Nobuhide Shibusawa Yoshie Endo Naoki Morimoto Ichiro Takahashi Takashi Miura Mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures
description	Abstract The median palatal suture serves as a growth center for the maxilla; inadequate growth at this site causes malocclusion and dental crowding. However, the pattern formation mechanism of palatal sutures is poorly understood compared with that of calvarial sutures such as the sagittal suture. In the present study, therefore, we compared the morphological characteristics of sagittal and palatal sutures in human bone specimens. We found that palatal suture width was narrower than sagittal suture width, and the interdigitation amplitude of the palatal suture was lower than that of the sagittal suture. These tendencies were also observed in the neonatal stage. However, such differences were not observed in other animals such as chimpanzees and mice. We also used a mathematical model to reproduce the differences between palatal and sagittal sutures. After an extensive parameter search, we found two conditions that could generate the difference in interdigitation amplitude and suture width: bone differentiation threshold $$v_c$$ v c and growth speed c. We discuss possible biological interpretations of the observed pattern difference and its cause.
format	article
author	Nobuhide Shibusawa Yoshie Endo Naoki Morimoto Ichiro Takahashi Takashi Miura
author_facet	Nobuhide Shibusawa Yoshie Endo Naoki Morimoto Ichiro Takahashi Takashi Miura
author_sort	Nobuhide Shibusawa
title	Mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures
title_short	Mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures
title_full	Mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures
title_fullStr	Mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures
title_full_unstemmed	Mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures
title_sort	mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/43ab4ea2026f4c2e969859eae41abfce
work_keys_str_mv	AT nobuhideshibusawa mathematicalmodelingofpalatalsuturepatternformationmorphologicaldifferencesbetweensagittalandpalatalsutures AT yoshieendo mathematicalmodelingofpalatalsuturepatternformationmorphologicaldifferencesbetweensagittalandpalatalsutures AT naokimorimoto mathematicalmodelingofpalatalsuturepatternformationmorphologicaldifferencesbetweensagittalandpalatalsutures AT ichirotakahashi mathematicalmodelingofpalatalsuturepatternformationmorphologicaldifferencesbetweensagittalandpalatalsutures AT takashimiura mathematicalmodelingofpalatalsuturepatternformationmorphologicaldifferencesbetweensagittalandpalatalsutures
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Mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures

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